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This review examines the potential of apigenin and ellagic acid as adjunct or alternative treatments for PCOS, but reports no new clinical results and highlights the need for further trials to confirm their efficacy and optimize dosing and delivery.

This systematic review reported that probiotics, prebiotics, synbiotics, postbiotics, and dietary supplements may improve hair density and reduce dandruff severity in individuals with scalp disorders, potentially by modifying inflammation, oxidative stress, and microbiota composition; however, variability across studies limits the strength of these conclusions.

In this review, researchers examined the concentration of cortisol in scalp hair of individuals with alopecia areata to explore its relationship with disease variables, as cortisol in hair can indicate chronic stress, which may impact alopecia areata pathogenesis.

In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.

This study reviewed literature on hair growth and found that external factors like pollution, stress, and nutrition can adversely affect hair, concluding that a multifactorial approach and personalized nutrition monitoring are essential for effective hair loss therapy.

This review discusses existing literature on the effects of isoflavone in alleviating PCOS symptoms, highlighting its potential benefits in reducing testosterone levels, improving metabolic profiles, and lowering inflammation and oxidative stress, although findings have been both significant and non-significant.

This study observed that middle-aged women with Polycystic Ovary Syndrome who practiced yoga Nidra for twelve weeks experienced improvements in stress, anxiety, and depression compared to a control group that did not participate in any intervention.

This review examines the potential link between polycystic ovary syndrome and reproductive cancers, highlighting possible underlying causes as well as the ongoing debate over the cancer risk in these patients.

This article reviews the use of hair cortisol concentration as a biomarker to assess long-term stress in both animals and humans, but it reports no new experimental results.

This review discusses alopecia, its pathophysiology, nanotechnology-based drug delivery systems, and related quality of life issues, without reporting new clinical results.

In this case report, a 17-year-old girl with secondary amenorrhea was evaluated for PCOS, highlighting the importance of assessing abnormal menstrual patterns for underlying conditions, and suggesting that hormonal birth control and lifestyle changes can help manage symptoms.

This review examines the development of cardiovascular risk factors related to testosterone levels in PCOS women and reports no new clinical results.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

In this study, socially defeated mice showed increased alcohol consumption, and CRF-R1 antagonism selectively reduced drinking in these mice, suggesting a potential treatment target for stress-related alcohol use disorders.

This chapter reviews existing knowledge about melatonin's MT₁ and MT₂ receptors in human tissues, discussing their established and potential functions, but reports no new clinical findings.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

This article reviews dietary recommendations for managing polycystic ovary syndrome and provides evidence that diet changes can improve the androgen profile in affected women, but it reports no new clinical results.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

This review discusses normal menstrual variations and common menstrual disorders in adolescent girls, focusing on symptoms, evaluation, and management, but does not present new clinical results.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

The study found that finasteride increased endoplasmic reticulum stress and reduced fertility in rats, effects that were alleviated by the administration of DA-9401.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

This review discusses the prevalence and management of polycystic ovary syndrome in women, particularly noting gaps in understanding its presence in adolescents, and reports no new clinical findings.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

This article provides an overview of ovulation disorders, discussing ovarian, hypothalamic, and endocrine defects but reports no new clinical findings.

This review outlines the biological effects of various placental extracts, noting their reported antioxidant, anti-inflammatory, and immunomodulatory activities, but highlights that the relationship between these effects and the extracts' specific contents remains unclear.

This study found that higher levels of cortisol (F) and cortisone (E) in hair before stroke onset were significantly associated with post-stroke depression and anxiety, suggesting they could serve as potential predictors for these mood disorders.

Stress during pregnancy can thin fetal skin.

This review posits that alopecia in PCOS results from the interaction between local follicular signaling failures, insulin resistance, inflammation, and genetic predispositions, rather than solely from androgen excess, and recommends a systems-level framework for its management.