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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

TRH stimulates human hair growth and extends the hair growth phase.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Combining cosmetic procedures with lifestyle changes improves antiaging results.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Some skin diseases and their treatments can negatively affect male fertility.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.