March 2021 in “Annals of Translational Medicine” This report presents two cases of systemic lupus in male patients with a distinct form of alopecia that combines both scarring and non-scarring elements, highlighting the variability in lupus-related hair loss presentations.
March 2012 in “Journal of The American Academy of Dermatology” This study found that white females with female pattern hair loss had higher hair density in the occipital scalp area, while Asian females had thicker hair diameters in both frontal and occipital areas.
October 2004 in “Kafrelsheikh Veterinary Medical Journal” In this study, buffalo calves fed only corn silage showed deficiencies in copper, zinc, selenium, and vitamin A, along with improved physiological conditions after dietary supplementation and treatment.
July 2004 in “British Journal of Dermatology” This paper summarizes the main findings presented in the plenary sessions of the British Journal of Dermatology, July 2004 issue, and provides no new research results.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This paper reviews the diverse skin, nail, and hair changes caused by medications, highlighting hyperpigmentation, alopecia, and nail structural alterations, but reports no new data.
This case study reports significant clinical and hormonal improvement in a 21-year-old woman with HAIR-AN syndrome after nine months of treatment with oral contraceptives and spironolactone.
1 citations
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April 2018 in “Lasers in Surgery and Medicine” This review summarizes late-breaking abstracts from the American Society for Laser Medicine and Surgery, 2018, and reports no new clinical findings.
October 2019 in “European Journal of Dermatology” This review discusses the diagnosis and treatment of pityriasis rubra pilaris and reports no new clinical results.
9 citations
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November 2015 in “JAMA dermatology” This case study describes an elderly woman with distinctive black hair patches and scalp pigmentation, but it does not provide a diagnosis or new findings.
114 citations
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April 2004 in “International Journal of Dermatology” Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.
10 citations
,
September 1994 in “International Journal of Dermatology” This case report describes three Iranian men with gradual reddish-brown pigmentation on their cheeks and preauricular areas since childhood, unresponsive to sunblocks and topical steroids.
This study reported the case of a 30-year-old man with a bluish-grey scalp nodule that developed over a previously stable hairless plaque, revealing histopathological features consistent with epithelioid cell nests and spindle-shaped dermal melanocytes embedded in collagen.
9 citations
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June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” This study examined skin biopsies from a woman with Addison disease and found melanocytic hyperpigmentation in the epidermis, with a notable melanocyte/keratinocyte ratio indicating increased melanocyte presence in the arm compared to the thigh.
13 citations
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January 2009 in “The Open Dermatology Journal” This article describes a case of oral pigmentation that posed a diagnostic challenge in determining Addison’s disease and includes a brief review, reporting no new clinical results.
7 citations
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March 2003 in “PubMed” This study reported that in men with androgenic alopecia, a distinct subclinical hyperpigmentation pattern was observed in the scalp, associated with baldness severity and possibly linked to local melanin production by pilosebaceous units.
21 citations
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November 1981 in “Archives of Dermatology” This study hypothesizes that postinflammatory hyperpigmentation in ashy dermatosis may result from basal cell apoptosis, as evidenced by consistent histologic findings across nine patients.
January 2023 in “Indian Dermatology Online Journal” This article reviews the indications for micropigmentation in dermatological conditions like stable vitiligo and alopecia, but presents no new clinical results.
June 2021 in “Asian Journal of Medical Sciences” This case study highlights that vitamin B12 deficiency can cause reversible hyperpigmentation, illustrated by a vegetarian female patient whose skin lesions improved after treatment.
March 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this case report, the authors found that pigmented demodicosis, caused by Demodex mites, led to facial hyperpigmentation in a 16-year-old male and showed significant improvement with oral isotretinoin and topical ivermectin treatment.
4 citations
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December 2013 in “The Journal of Dermatology” This letter to the editor discusses a case of delayed-onset pachyonychia congenita linked to a new mutation in keratin 6b but presents no new research findings.
56 citations
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December 1978 in “The Journal of Dermatologic Surgery and Oncology” This study reported successful and cosmetically acceptable repigmentation of leukoderma in three patients using minigrafts of normally pigmented, autologous skin.
April 2019 in “Journal of Investigative Dermatology” This study reported that gain-of-function mutations in TRPV3 lead to hair loss in mice by disrupting inner root sheath keratinocyte differentiation, ultimately causing follicular keratinocyte stem cell exhaustion and permanent follicle disruption.
2 citations
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October 2016 in “Nutrition in clinical practice” This case report describes a rare instance of reversible melasma-like hyperpigmentation linked to vitamin B12 deficiency due to pernicious anemia, and explores possible mechanisms for this association.
13 citations
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January 2014 in “Postępy Dermatologii i Alergologii” This report describes four cases of patchy, non-scarring alopecia areata that spared gray hairs and affected only pigmented hairs.
1 citations
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July 2018 in “JAMA dermatology” This abstract contains navigation and subscription information for JAMA Dermatology and reports no new clinical findings.
21 citations
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October 2007 in “Australasian Journal of Dermatology” This case study reported that a 62-year-old woman with alopecia areata experienced significant hair regrowth with completely non-pigmented white hair following a 2-month course of oral prednisolone.
16 citations
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February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
23 citations
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April 2002 in “Journal of the American Academy of Dermatology” This case report describes persistent depigmented hair regrowth from an alopecia areata patch, challenging the previous assumption that such regrowth is only temporary.
June 2026 in “Dermatology and Therapy” This review provides an analysis of topical treatments with clinically proven efficacy for managing hyperpigmentation and concludes that the most effective approach is using combined therapies that target multiple aspects of skin pigmentation physiology.
This study describes vitiligo as a chronic disorder where genetic, environmental, and immune factors contribute to skin depigmentation, with associations to other autoimmune diseases and potential links to oxidative stress.