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Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Testosterone improves mood and thinking skills; finasteride has no effect.

Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Finasteride for hair loss can cause erectile dysfunction due to tissue fibrosis.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Lowering testosterone speeds up wound healing in male mice.

New treatments for male hypogonadism are effective and should be personalized.