research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
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research An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities
Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
research Mutation-Specific siRNA Knockdown of GJB2: Potential Gene Therapy for Keratitis-Ichthyosis-Deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research Stabilizing Mutations of KLHL24 Ubiquitin Ligase Cause Loss of Keratin 14 and Human Skin Fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research Paraoxonase 1 (PON1) L55M and Q192R Polymorphisms, Lipid Profiles, and Psoriasis
The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.
research Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-Mediated Genome Editing in Epidermal Stem Cells
Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.
research Transcriptomics Identifies Potential Novel Therapeutic Targets in Androgenetic Alopecia
Found new possible treatments for hair loss.
research Topical Calcipotriol for Preventive Treatment of Hypertrophic Scars
Calcipotriol doesn't prevent hypertrophic scars, but keratinocyte activation is important in scar formation.
research Effects of Ginsenoside Rb1 on Hypertrophic Scar Remodeling in Rabbit Model
Ginsenoside Rb1 may help remodel hypertrophic scars effectively at a dose of 0.56 mg.
research The Expression of Melatonin Receptor in Human Hypertrophic Scar
Melatonin might help treat thick scars.
research The Effect of Inflammatory Cytokines on the Risk of Hypertrophic Scar: A Mendelian Randomization Study
Certain proteins can either protect against or increase the risk of hypertrophic scars.
research Acitretin: A Good Treatment Option for Hypertrophic Lichen Planus
Acitretin effectively treats severe hypertrophic lichen planus.
research Suppression of Fibroblast Proliferation and Lysyl Hydroxylase Activity by Minoxidil
Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes
Blood vessels and specific genes help turn cartilage into bone when bones heal.
research The Surgical Management of Extensive Cases of Acne Keloidalis Nuchae
Excision with primary closure is an excellent treatment for extensive acne keloidalis nuchae.
research Effects of Minoxidil on Cultured Human Skin Fibroblasts
Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
research Clinical Study of Twenty-Nail Dystrophy in Korea
The Korean study found that twenty-nail dystrophy mainly affects adults, more often women, and has five distinct types with different clinical progressions.
research The Pathological Culprit of Neuropathic Skin Pain in Long COVID-19 Patients: A Case Series
Long COVID-19 patients with skin pain might have a nerve condition that responds to a medication called gabapentin.
research Fibroblast Heterogeneity in Healthy and Wounded Skin
Different types of fibroblasts exist in skin and understanding them can help improve wound healing and treat scars.
research Cutaneous Manifestations at Saphenous Vein Harvest Site Among Iraqi Patients with Coronary Artery Bypass Graft
Many Iraqi patients had skin problems at the site where a vein was taken for heart surgery.
research Krox20 Expression in Abnormal Scars: An Immunohistochemical Study
Krox20 overexpression in fibroblasts may play a role in abnormal scar formation and could be a target for new treatments.
research Apoptotic Dysregulation Mediates Stem Cell Competition and Tissue Regeneration
Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
research Mutational Analysis of Mitochondrial DNA in Maternal Inheritance of Polycystic Ovarian Syndrome
Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.
research The Role of YAP1 in Regeneration of Human Skin and in Pathological States
YAP1 is important for skin regeneration and may affect skin disorder treatments.
research Aesthetic Surgery Applications for Adipose-Derived Stem Cells
Adipose-derived stem cells show promise for cosmetic treatments but need more research.
research Journal of Cosmetic Dermatology Editorial September 2021
The editorial stresses the importance of COVID-19 vaccination and ongoing contributions to the journal.
research Hair-Thread Tourniquet Syndrome of Labia: A Case Report
Removing hair wrapped around the labia quickly prevents serious tissue damage.
research Anesthetics Prior to Keloid Injections: A Painless Approach
Using lidocaine before keloid injections makes the treatment more comfortable for patients.
research Robotic Hair Transplantation Surgery
Robotic hair transplantation surgery is generally effective with high satisfaction rates and minimal complications.
research The Place of Intralesional Steroid Therapy in Dermatology
Intralesional steroid therapy is useful for treating various skin conditions.