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A 12-year-old girl in Saudi Arabia with Focal dermal hypoplasia showed skin and dental symptoms, highlighting the condition's variability and the need for personalized treatment.

Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.

Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.

Some plant-based ingredients may help with hair growth and care, but more research is needed to confirm their effectiveness.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.

Minoxidil and finasteride combined can effectively treat hair loss.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Hair growth is cyclic and influenced mainly by local factors.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.