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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.

Early diagnosis and aggressive treatment are crucial for managing SLE-related pancreatitis in children.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Higher doses of isotretinoin may lead to more hair loss.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Certain nutrients can help keep skin healthy as we age.

Thyroid problems are linked to various skin issues, and checking thyroid health is important for people with certain skin conditions.

Psychotropic medications can cause skin problems but also treat some skin conditions.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

Recognizing rare causes of MASLD is crucial for effective treatment and preventing complications.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.

PCOS treatment should address both symptoms and metabolic risks, starting with lifestyle changes and possibly including medication.

Balding men have higher heart disease risk.

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

New treatments for hair loss show promise but need more research to confirm safety and effectiveness.

Birth control pills can help manage acne, but dermatologists should know their skin-related side effects, especially when prescribing drugs that can harm unborn babies.

JAK inhibitors for alopecia areata are linked to minor side effects like headache and acne, but not to an increased risk of serious adverse events.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.

Glycerol is essential for skin hydration in mice without sebaceous glands.