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This review discusses the biology of antiandrogens and highlights available bioassay models to predict their therapeutic effects on human skin, reporting no new clinical results.

In this study, researchers found that knockdown of ABCA5 in primary human hair follicle keratinocytes disrupted cholesterol homeostasis and transportation, suggesting its potential role in hair growth disorders by affecting intracellular cholesterol compartmentalization and LXR-mediated transcriptional activity.

This study found that Minoxidil had biphasic effects on normal human keratinocytes, stimulating proliferation at micromolar doses, but showing antiproliferative, pro-differentiative, and cytotoxic effects at millimolar concentrations.

This study found that minoxidil effectively manages various types of severe hypertension but can cause side effects such as sodium retention and tachycardia.

This review discusses the use of low-dose oral minoxidil for patterned hair loss and reports it may offer improved compliance and safety compared to topical minoxidil, but provides no new clinical findings.

In this placebo-controlled clinical study, a cream containing 4% capryloyl glycine and 1% glycine soy‐fermented extract effectively inhibited ODC1 activity and improved hypertrichosis in 91.7% of Caucasian female patients on the forearms, whereas no improvement was observed with the placebo.

This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

UV light might cause excessive hair growth by increasing PGE2 in the skin.

This study found no significant differences in lectinhistochemical characteristics of the dorsal skin epidermis between hypotrichotic WBN/Ila-Ht rats and Wistar rats, except for varying lectin binding intensity.

This case report suggests that hypertrichosis might be an early sign of porphyria cutanea tarda, as illustrated by a woman whose symptoms improved after stopping estrogen-containing oral contraceptives.

This review discusses cyclosporine A's mechanisms of action and side effects compared to tacrolimus in renal transplantation, but it reports no new experimental results; the authors highlight implications for cardiovascular risk management.

This article reviews how various drugs may cause hair loss, stimulate growth, or alter hair characteristics, but reports no new clinical results; drug-induced hair loss is typically reversible.

This study found various ABC transporters are transcribed in human hair follicles, suggesting their possible role in HF biology and potential for new therapeutic interventions.

This article discusses various forms of alopecia, emphasizing the need for light microscopy to investigate hair shaft disorders, and does not report new clinical findings.

This study found that unilateral topical latanoprost use for glaucoma was associated with hypertrichosis and increased pigmentation of eyelashes in the treated eye compared to the untreated eye.

This article reports a case where the IOP-lowering drug bimatoprost was associated with eyelash hypertrichosis.

In this case report, a 25-year-old transgender woman on testosterone-blocking therapy developed generalised hypertrichosis after starting ciclosporin for severe plaque psoriasis, illustrating that ciclosporin can induce this side effect even under androgen suppression.

This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.

This study described specific skin and hair follicle abnormalities in three Japanese patients with Cantu syndrome, which may relate to the regulation role of SUR2 in hair follicle growth.

A woman with frontal fibrosing alopecia experienced unusual hair growth after using a specific topical lotion.

In this study, five women with minoxidil-induced hypertrichosis achieved complete hair removal using a calcium thioglycolate depilatory agent, with minimal or no skin irritation.

Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.

An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.

This study reported that sulfotransferase activity in plucked hair follicles can predict treatment response to 5% topical minoxidil in women with androgenetic alopecia with high sensitivity and specificity.

This study found that a combination of Trichogen and climbazole may inhibit protease activity and increase the force required to remove human hair, suggesting potential to reduce excessive hair shedding.

This study found that spironolactone therapy may reduce hair width in prepubertal girls with simple hypertrichosis, though its long-term efficacy and safety remain uncertain.

This case report describes a 54-year-old woman who developed hypertrichosis around a leg ulcer while using PGE1 ointment, suggesting a potential side effect of the treatment.

This case report describes a 16-year-old girl with severe generalized gingival fibromatosis and hypertrichosis, who underwent successful treatment through gingivectomy, with uneventful healing observed over an eight-month follow-up.

In this study, facial hypertrichosis occurred in 10% of women treated with isotretinoin for acne, but it resolved spontaneously after the treatment ended.

In this study, minoxidil was found to suppress the activity of normal human T-lymphocytes in vitro, though the physiological relevance of this effect remains uncertain.