113 citations,
July 2020 in “Communications biology” Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
96 citations,
August 1995 in “Bone” Vitamin D3 is important for bone health and may help treat various diseases beyond bone-related conditions.
84 citations,
February 2013 in “Clinica chimica acta” Hair mineral analysis might help diagnose diseases early, but standard methods are needed.
65 citations,
September 2017 in “British Journal of Cancer” Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.
65 citations,
February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
64 citations,
December 1990 in “Journal of the American Academy of Dermatology” Cyclosporine can treat skin conditions but needs careful monitoring for side effects.
59 citations,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
54 citations,
February 2012 in “Pediatrics in Review” Pediatric systemic lupus erythematosus is a severe autoimmune disease in children requiring early diagnosis and comprehensive management.
43 citations,
December 2008 in “PLOS ONE” Medical terms make new health issues seem more serious but don't affect views on well-known conditions.
42 citations,
January 2019 in “Frontiers in Immunology” A blood pressure drug, diltiazem, may also help treat influenza.
38 citations,
January 2014 in “International Journal of Endocrinology” Adrenal disorders can cause lasting brain and behavior issues in children.
37 citations,
April 2002 in “The American Journal of Medicine” St. John's Wort can cause dangerous high blood pressure if taken with certain foods.
33 citations,
August 2013 in “Lupus” SLE patients in eastern Saudi Arabia have a generally good prognosis despite multi-organ involvement.
30 citations,
July 2019 in “Endocrinology” Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
29 citations,
July 2020 in “Journal of The American Academy of Dermatology” Men with severe balding have a higher risk of getting very sick from COVID-19.
28 citations,
February 2020 in “Clinical Ophthalmology” Certain medications and patient factors increase the risk of Intraoperative Floppy Iris Syndrome during cataract surgery, but with careful planning and technique adjustments, complications can be minimized.
26 citations,
April 2009 in “Australasian Journal of Dermatology” Spironolactone successfully treated hair loss in a 9-year-old girl.
25 citations,
December 2001 in “Expert Opinion on Pharmacotherapy” Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
24 citations,
June 2010 in “Clinics in Dermatology” Taking too many vitamin and mineral supplements can cause serious health problems.
23 citations,
December 2008 in “Current medicinal chemistry” Stimulating sensory neurons can increase IGF-I production, which may help treat various diseases and improve tissue health.
23 citations,
March 1988 in “Biochemical Pharmacology” Minoxidil stops cells from making prostacyclin, which may help with hair growth. More research is needed.
22 citations,
March 2018 in “International Ophthalmology” Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.
20 citations,
December 2021 in “Plants” Tamarix aphylla may be effective for various medical conditions, but more research is needed to confirm its safety and effectiveness.
20 citations,
January 2000 in “Dermatologic Clinics” New psoriasis treatments are effective but come with side effects and risks.
17 citations,
July 2015 in “Biomolecules and Biomedicine” High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.
15 citations,
June 2019 in “Experimental Dermatology” Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
14 citations,
April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
13 citations,
January 2019 in “Journal of the American Academy of Dermatology” Pityriasis rubra pilaris significantly worsens quality of life more than many other health conditions.
12 citations,
April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.