179 citations,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
91 citations,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
81 citations,
November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
55 citations,
May 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
46 citations,
May 2015 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
44 citations,
September 2014 in “Cell Death & Differentiation” Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
44 citations,
June 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
42 citations,
November 2002 in “The American journal of pathology” Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
16 citations,
May 1998 in “International Journal of Dermatology” Stress hormones like cortisol may trigger psoriasis flare-ups.
14 citations,
July 2014 in “Experimental Cell Research” The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
13 citations,
October 2012 in “Free Radicals and Antioxidants” The red Hibiscus rosa-sinensis flower has the highest antioxidant activity.
8 citations,
June 2013 in “Journal of Investigative Dermatology” Different problems with hair stem cell renewal can lead to hair loss.
December 2014 in “Annals of psychophysiology” Power-enhancing drugs can cause mood swings, aggression, anxiety, and physical side effects, questioning their overall benefits.
April 2005 in “Aktuelle Dermatologie” Shampoos have evolved to address individual hair and scalp needs, and treatments like Minoxidil and Finasteride help with hair loss.
45 citations,
April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
37 citations,
November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
479 citations,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
94 citations,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” EGF controls hair growth by regulating hair follicles' growth phases.
1 citations,
February 2022 in “Cell Biology International” Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
42 citations,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
May 2022 in “International Journal of Health Sciences (IJHS)” Hibiscus Rosa Sinensis Linn is a tropical plant used for various medicinal purposes due to its many beneficial properties and components.
13 citations,
March 1997 in “Research in Veterinary Science/Research in veterinary science” Epithelial proliferation and hyperkeratosis are linked to gastric ulcers in pigs.
1 citations,
September 2011 in “British Journal of Dermatology” Malassezia yeast plays a key role in dandruff and seborrhoeic dermatitis.
344 citations,
May 2018 in “EMBO journal” Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
14 citations,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.
16 citations,
December 2008 in “International Journal of Dermatology” Long-term use of pyrithione zinc shampoos remains effective for scalp seborrheic dermatitis, with decreased effectiveness likely due to not following treatment instructions rather than the treatment itself.
34 citations,
July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.