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Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

K6hf is a unique protein found only in a specific layer of hair follicles.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

EGFR helps control how hair grows and forms without needing p53 protein.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Histone modification is key in treating chronic inflammatory skin diseases.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Lower SMAD2/3 activation predicts more severe skin cancer.

The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Common noncancerous skin diseases have various treatments, including topical applications, light therapy, surgery, and medications, with psychological support being important.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Platelet-rich plasma treatment may safely and effectively reduce skin lesions in psoriasis and atopic dermatitis.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

People with certain skin diseases have higher levels of the hormone prolactin in their blood.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Adipokines affect skin health and could be targeted for treating skin diseases.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Notch signaling disruptions can cause various skin diseases.

The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.