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The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

K6hf is a unique protein found only in a specific layer of hair follicles.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Mutant mice help researchers understand hair growth and related genetic factors.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Inactive hair follicle stem cells help prevent skin cancer.

RANK-RANKL signaling is essential for hair growth and skin health.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

FLRG and follistatin have different roles in wound healing.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

A cream with a specific hormone blocker increases hair growth in mice.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

A mutation in the FAM83G gene is linked to skin and hair abnormalities in two related individuals.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

Cilostazol may help hair grow and could be a new treatment for hair loss.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.