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Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Hair follicle cells can help heal wounds and study skin diseases.

COX2 and ATP synthase control the size of hedgehog spines.

The exact identity of skin stem cells and how skin cells differentiate is not fully known.

Finasteride and low-level laser therapy are similarly effective for frontal pattern hair loss.

IL-17 inhibitors for psoriasis may cause unexpected hair loss.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Lower SMAD2/3 activation predicts more severe skin cancer.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

Glucosylceramides are essential for healthy skin and proper wound healing.

KLF4 is important for keeping hair follicle stem cells inactive.

Nrf2 helps protect skin from damage but too much can cause skin problems.

Betamethasone dipropionate reduced skin thickness, fish oil increased it, and combined treatment had no significant effect.

Topical glucocorticoids thin the skin and change collagen structure.

Etretinate therapy can cause hair loss by disrupting the hair growth cycle.

Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.