34 citations,
August 2018 in “Cancer research” Fixing DNA errors is crucial to prevent skin cancer.
Ribonucleotide excision repair is crucial to prevent skin cancer.
Ribonucleotide excision repair is crucial to prevent skin cancer.
Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.
October 2014 in “Cancer research” Blocking mTORC1 reduces skin tumor growth in mice.
July 2012 in “European journal of cancer” MPA increases cancer spread by boosting Eph A2 activity.
50 citations,
February 2004 in “Genomics” A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
February 2024 in “Journal of Investigative Dermatology” Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.
research Acne
231 citations,
April 2005 in “The New England Journal of Medicine” Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.
46 citations,
September 2016 in “Clinical, Cosmetic and Investigational Dermatology” Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
2 citations,
November 2018 in “Cell Stem Cell” The research found a new way to heal chronic skin ulcers by turning certain cells into skin tissue using specific factors.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
721 citations,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
185 citations,
June 2014 in “Journal of Investigative Dermatology” A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
93 citations,
April 2003 in “Proceedings of the National Academy of Sciences of the United States of America” Fatty acid transport protein 4 is essential for skin and hair development.
87 citations,
February 2004 in “Plastic and Reconstructive Surgery” Hair follicle stem cells helped heal a severe scalp burn without needing traditional skin grafts.
81 citations,
November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
59 citations,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
47 citations,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
47 citations,
January 2015 in “Dermatology” The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.
44 citations,
June 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
21 citations,
January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Acne is an important sign of androgen excess disorders in women.
15 citations,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
14 citations,
February 2014 in “Experimental Cell Research” The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
13 citations,
October 2012 in “Free Radicals and Antioxidants” The red Hibiscus rosa-sinensis flower has the highest antioxidant activity.
11 citations,
August 2013 in “International Journal of Cosmetic Science” The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.
10 citations,
August 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Actinic superficial folliculitis is a unique skin condition caused by intense heat and sweating.
8 citations,
May 2013 in “Journal of Investigative Dermatology” Different problems with hair stem cell renewal can lead to hair loss.