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This study observed that heavy draft horses with verrucous pastern dermatitis showed significantly increased expression of keratins K6 and K16, suggesting a phylogenetically conserved keratin expression pattern in response to skin inflammation and proliferation.

This study found that Gsdma3 mutations in mice led to thicker skin and longer hair infundibula, possibly by negatively regulating β-catenin expression in the epidermis.

This study highlights the importance of recognizing oral lesions in diagnosing syphilis, as illustrated by three reported cases.

This study found that high doses of TCB caused severe toxicity in cotton top marmoset monkeys, with clinical and histological changes similar to those in humans and other primates exposed to PCBs.

This study found that NGAL expression increased in calcium-induced keratinocyte differentiation in vitro and was highly elevated in psoriasis-like skin conditions and skin cancers, suggesting a role in skin hyperplasia and homeostasis.

This study found that deletion of c-Jun and JunB in mouse bulge hair follicle stem cells was sufficient to trigger psoriasis-like skin disease through thymic stromal lymphopoietin signaling.

In this study, mange lesions with alopecia and crusts in masked palm civets in Japan were caused by the mite Notoedres cati.

This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.

This study found that the enzyme A20 helps regulate EDAR-induced NF-κB signaling in mice, preventing ectodermal abnormalities like disheveled hair and assuring proper skin and appendage development.

This review discusses the role of Hedgehog signaling in epidermal and hair follicle development and its involvement in basal cell carcinoma, without reporting new empirical findings.

This study found that Gynostemma pentaphyllum hydrodistillate and Damulin B exert significant anti-photoaging effects in UVB-irradiated models by reducing oxidative stress, improving ECM integrity, and enhancing skin hydration and elasticity.

In randomized controlled trials, this research reports that cyclosporin is as effective as glucocorticoids for treating canine atopic dermatitis and has potential benefits for other immune-mediated skin conditions in dogs.

This article reviews the diverse clinical applications of oral contraceptives beyond birth control, suggesting their effectiveness in treating various female health disorders and conditions.

This review discusses the use of testosterone therapy for low libido in women, noting mixed evidence on breast cancer risk and a lack of long-term safety data.

This study found that CI-1033 caused skin lesions in rats that resemble effects seen in humans receiving EGF receptor inhibitors, suggesting this animal model can help explore the mechanisms behind this cutaneous toxicity.

This review discusses the efficacy and safety of oral finasteride for treating male pattern baldness and the potential persistent side effects, but no new results are reported.

This study detected sarcoptic mange in five free-ranging raccoon dogs in Schleswig-Holstein, Germany, with four showing severe skin lesions and potential secondary bacterial infections, suggesting they may act as vectors in disease spread.

In this study, conditional deletion of BRD4 in OX40-expressing cells of mice led to alopecia, dermatitis, and loss of hair follicle stem cell function, revealing BRD4's role in skin inflammation and stem cell regulation.

This infographic reviews the pathophysiology and complications of PCOS, illustrating how genetic and environmental factors contribute to its development, and highlights associated metabolic and neuroendocrine effects.

In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.

This report describes a case of Goltz syndrome in a 12-year-old Saudi girl, highlighting the variability in symptoms and the importance of documenting such rare syndromes.

This case report identified a 6-month-old girl with congenital generalized hypertrichosis and gingival hyperplasia, where a de novo CNV on chromosome 17q24.2-24.3 was associated with reduced expression of ABCA5 and SOX9.

This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.

In this study, the authors found that targeting mTORC1 with rapamycin inhibited TPA-induced skin tumor promotion by affecting keratinocyte proliferation, including critical stem cell populations in the mouse epidermis.

This review discusses the biochemical properties and clinical significance of 5 alpha-reductase isozymes and reports no new clinical results.

This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.

This study found that Epstein pearls and Mongolian spots are the most common skin lesions in newborns in India, influenced by interracial, environmental, and hormonal factors.

This study found that distinct isoenzymes of 3 beta-hydroxysteroid dehydrogenase are expressed in human adrenals and gonads compared to the placenta and skin.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

This review discusses hormonal changes during menopause, emphasizing the relative androgen excess and the role of insulin resistance, and reports no new clinical findings.