research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
Patched1 helps prevent tumors by controlling cell growth.
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research Vulvar Problems in Elderly Women
Older women often have vulva issues due to less estrogen, which can be misdiagnosed and lead to wrong treatments.
research The Extract of Thuja Occidentalis Semen Inhibited 5α-Reductase and Androgenetic Alopecia in B6CBAF1/J Hybrid Mice
Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Tracing the Cellular Origin of Cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Alopecia
The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
research Wound Healing With Topical BRAF Inhibitor Therapy in a Diabetic Model Suggests Tissue Regenerative Effects
A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.
research Metallothionein Expression During Wool Follicle Development in Fetal Sheep
Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
research Minoxidil and Male-Pattern Alopecia: A Potential Role for a Local Regulator of Sebum Secretion with Vasoconstrictive Effects?
Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.
research Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis
Overexpressing follistatin in mice delays wound healing and reduces scar size.
research Reversible Hypopigmentation of Hair Secondary to Vitamin B12 Deficiency
Vitamin B12 deficiency can cause reversible hair color loss in children.
research Disorders of the Hair and Nails
The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
research Critical Stages of Hair Development and Pigmentation in the Mouse
Hair growth and pigmentation in mice involve specific stages crucial for research.
research Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in Males
Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
research Solitary Pedunculated Multicystic Viral Plaque Associated with Canine Papillomavirus 18 in a British Bulldog
A British Bulldog had a unique viral plaque caused by Canine papillomavirus 18, different from typical tumors.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
research 14-3-3σ Is Required for Club Hair Retention
The 14-3-3σ gene is essential for preventing hair loss.
research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin
Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
research Primary Hypothyroidism and Thyroid Goiter in an Adult Cat
The cat's hypothyroidism was successfully managed with levothyroxine, leading to a stable condition.
research Diseases of the Ear Pinna
The document discusses various diseases of the outer ear, categorized by symptoms like redness, crusts, bumps, pus-filled lesions, lumps, ulcers, and hair loss.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research What Do We Know About 5-Alpha Reductase Inhibitors?
Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.
research Diagnostic Exercise: Severe Bilaterally Symmetrical Alopecia in a Horse
A horse with severe hair loss was diagnosed with alopecia areata and a yeast infection.
research Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center
Most patients with frontal fibrosing alopecia had facial bumps, with Hispanic/Latino and premenopausal women being more affected, suggesting a more severe condition.
research Histopathological Findings and Proliferative Activity of Canine Sebaceous Gland Tumors with a Predominant Reserve Cell Population
High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.
research The Biology of Hair Diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Exploiting the Origins of Ras-Mediated Squamous Cell Carcinoma to Develop Novel Therapeutic Interventions
Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.