research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
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research Stress-Related Skin Disorders
Stress can worsen skin conditions by affecting hormone levels and immune response.
research Editor's Evaluation: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Innate Type 2 Immunity Controls Hair Follicle Commensalism by Demodex Mites
Type 2 immunity helps control mite growth in hair follicles, preventing damage.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
research YAP And TAZ Are Essential For Basal And Squamous Cell Carcinoma Initiation
YAP and TAZ proteins are necessary for the development of two types of skin cancer.
research Fatty Acids and Related Lipid Mediators in the Regulation of Cutaneous Inflammation
Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Expression of EZH2 in the Skin of Developing Human Fetuses and Adults: A Comparative Study
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research Towards a Molecular Understanding of Hair Loss and Its Treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Genetic Basis of Skin Appendage Development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research The Role of Smads in Skin Development
Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
research Developing Stratified Epithelia: Lessons from the Epidermis and Thymus
The skin and thymus develop similarly to protect and support immunity.
research Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype
SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
research Histocompatibility and Long-Term Results of Follicular Unit-Like Wigs After Xenogeneic Hair Transplantation: An Experimental Study in Rabbits
The wigs made from human hair and polypropylene were mostly well-tolerated and durable in rabbits, suggesting they could be a new option for people with extensive hair loss.
research Early Inductive Events in Ectodermal Appendage Morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research Nutraceuticals: A Review
Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research Lithium Therapy Associated with Hidradenitis Suppurativa: Case Report and Review of Dermatologic Side Effects
Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.
research Endocrine-Skin Interactions
Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
research Over-Expression of Thymosin Beta4 Promotes Abnormal Tooth Development and Stimulation of Hair Growth
Too much thymosin beta4 causes weird teeth and more hair growth in mice.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Identification of Ultraviolet B Radiation-Induced MicroRNAs in Normal Human Dermal Papilla Cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.