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The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Big chain pharmacies in Pennsylvania charge significantly more for generic BPH medications than independent pharmacies, but independent pharmacies have more regional price variation.

Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.

Endurance exercise may help BPH by lowering hormones and inflammation.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.

Male pattern baldness may be an early sign of noncancerous prostate enlargement.

5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.

Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Castration significantly reduces prostate size and BPH symptoms.

Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.

Genetic mutations can affect female sexual development, requiring personalized medical care.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Hyperandrogenism, often causing excessive hair growth and acne, can be treated with methods like weight reduction, hair removal, various medications, and in the case of acne, topical treatments.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

Saw palmetto is not proven to improve urinary flow, prostate size, or hair loss.

Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.

The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

Most women with hirsutism have normal hormone levels and can be treated with cosmetic methods; obesity and PCOS are common causes, and treatments depend on the underlying issue.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Men with early balding may have a higher risk of prostate issues, and surgery for prostate cancer has a slight survival benefit over radiation.

Early balding may be a sign of future prostate problems.

Finasteride for hair loss may increase the risk of certain cancers and has side effects; better regulation and education on its use are needed.

Studying acne-related syndromes helps us understand acne causes and can lead to new treatments.

Biofeedback treatment for dysfunctional voiding in adults showed no symptom improvement.