6 citations
,
September 2022 in “Frontiers in pharmacology” In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.
108 citations
,
August 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.
This study highlights that azelaic acid, initially recognized for skin hypopigmentation, shows potential in treating various skin conditions due to its complex mechanisms, even though these are not yet fully understood, indicating a need for further research.
August 2026 in “Adolescencia e Saude” This study reviews various hyperpigmentation disorders, their causes, and evolving treatments, emphasizing the need for safe, effective cosmeceuticals particularly suited for adolescents, integrating botanical and phytochemical advancements with modern dermatological techniques.
February 2024 in “International Journal of Dermatology” This report highlights that scientific collaborations have led to a rise in publications focused on African skin and hair, which could inform the development of locally tailored products and awareness campaigns.
September 2015 in “Veterinary Dermatology” This study found that microneedling induced nearly complete hair regrowth in two Pomeranians with alopecia X, suggesting it may be a promising alternative treatment for similar hair cycle arrest disorders.
5 citations
,
April 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This article discusses the characteristics and pathogenesis of pseudofolliculitis barbae, particularly its prevalence in men of African and Asian descent, but presents no new research findings.
January 2024 in “Brazilian journal of veterinary pathology” In this case report, a 6-year-old spayed female Samoyed dog presented with non-pruritic alopecia and hyperpigmentation on the hips and back, with unremarkable bloodwork and negative Cushing's disease and skin tests.
8 citations
,
March 2015 in “Neuromuscular Disorders” This study found that adult patients with Myotonic Dystrophy type 1 exhibited a higher prevalence of various morphofunctional, inflammatory, and proliferative skin disorders compared to healthy controls.
138 citations
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June 2023 in “Molecules” This review examines various skin pigmentation disorders, their causes, and potential treatments, detailing 25 plants, 4 marine species, and 17 clinically tested topical and oral medications for managing these conditions.
May 2026 in “International Journal of Drug Delivery Technology” This case study highlights Erythromelanosis follicularis faciei et colli as an easily overlooked pigmentary disorder characterized by a distinctive triad requiring precise diagnosis for effective patient counseling and cosmetic management.
January 2016 in “Kafkas Journal of Medical Sciences” This study observed that dermatologists predominantly prescribed topical treatments for skin disorders in pregnant women, with pruritus and urticaria being the most common conditions.
January 2016 in “Dermatology Review” This review details various skin manifestations linked to different endocrine disorders but does not report any new clinical results.
2 citations
,
July 2018 in “Elsevier eBooks” This article discusses the uses and techniques of trichoscopy for hair and scalp disorders and reports no new clinical results.
April 2023 in “International journal of dermatology and venereology” This study observed distinct dermoscopic features in pityriasis versicolor that could aid in its differentiation from similar skin disorders.
2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” This article reviews the need for multicenter clinical trials to establish reference data for ultrasound screening protocols for Down syndrome and reports no new findings.
32 citations
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May 2023 in “Preprints.org” This review discusses the types, causes, and treatments for skin pigmentation disorders, examining clinically tested options including 25 plants, four marine species, and 17 medications.
12 citations
,
November 2020 in “Molecules” This study found that carvone, a plant-derived compound, decreases melanin content and inhibits melanoma cell proliferation through the cAMP pathway, suggesting potential benefits for treating melanomas and other hyperpigmentation disorders.
4 citations
,
February 2025 in “Pharmaceuticals” In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.
This study identified 92 novel regulators of melanogenesis, highlighting Aldehyde dehydrogenase 1A1 as a potential target for developing new treatments for hyperpigmentation disorders like melasma.
This study identified ALDH1A1 as a regulator of melanogenesis and suggests its inhibition, through agents like cyanamide, may be a promising therapeutic approach for treating hyperpigmentation disorders such as melasma.
9 citations
,
January 2018 in “Medical research archives” This review discusses the therapeutic use of photobiomodulation for various skin conditions, highlighting its efficacy in accelerating tissue repair, reducing inflammation, and treating pigmentary disorders and other skin diseases, but it reports no new clinical results.
4 citations
,
November 2019 in “Harper's Textbook of Pediatric Dermatology” This article reviews the skin, hair, nail, and mucosal changes linked to various pediatric endocrine disorders but provides no new clinical findings.
This review found that exposure to pollutants like PM, NOx, and PAHs is linked to various skin and hair disorders, indicating a need for cosmetics with natural adsorbents to reduce pollutant effects, achieving 30-55% removal efficiency.
April 2025 in “Our Dermatology Online” This article presents a case of a seventeen-year-old female with dermatopathia pigmentosa reticularis and emphasizes the importance of distinguishing its clinical features from other similar disorders, supported by dermoscopic and histopathological findings.
September 2017 in “Pediatric Dermatology” No results are reported in this correspondence published in Pediatric Dermatology, as it responds to prior communication about contact dermatitis related to alopecia and hyperpigmentation.
48 citations
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July 1992 in “International Journal of Dermatology” HIV can cause various nail and hair disorders, important for early diagnosis and treatment.
86 citations
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October 2017 in “Translational pediatrics” This review discusses how ophthalmic findings can reveal key endocrine disorders and reports no new clinical results, emphasizing the eye's role in diagnosing and managing systemic diseases like diabetes and Graves' ophthalmopathy.
12 citations
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October 1995 in “The Journal of Clinical Endocrinology & Metabolism” Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
14 citations
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January 2018 in “Skin Appendage Disorders” This case report suggests that identifying hyperpigmentation on the upper eyelid with specific dermoscopy patterns could help diagnose facial lichen planus pigmentosus without needing a facial biopsy.