60 citations,
September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.
369 citations,
June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
257 citations,
July 2018 in “Obstetrics & Gynecology” PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
222 citations,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
192 citations,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
135 citations,
April 2017 in “Advances in Clinical and Experimental Medicine” New treatments for PCOS show promise, including both medication and non-medication options.
99 citations,
August 2003 in “Fertility and Sterility” Too much male hormone is the main cause of Polycystic Ovary Syndrome.
85 citations,
June 2008 in “Annals of the New York Academy of Sciences” PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.
71 citations,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
60 citations,
October 2014 in “Journal of the American Academy of Dermatology” Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.
60 citations,
June 1997 in “Baillière's clinical obstetrics and gynaecology” PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
55 citations,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
49 citations,
June 2003 in “European journal of cardiovascular prevention & rehabilitation” Hair loss in middle-aged women is often linked to insulin resistance and a family history of hair loss, particularly from their fathers.
39 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
37 citations,
February 2007 in “Clinical Obstetrics and Gynecology” The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.
28 citations,
July 2017 in “Journal of Endocrinological Investigation” Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
28 citations,
November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
27 citations,
December 2013 in “Endocrinology” Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
26 citations,
January 2016 in “Indian journal of endocrinology and metabolism” Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.
23 citations,
March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
21 citations,
February 2021 in “Frontiers in Endocrinology” Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.
18 citations,
August 2012 in “Cutaneous and Ocular Toxicology” People with alopecia areata have higher insulin resistance.
18 citations,
December 2010 in “PubMed” People with early hair loss may have higher insulin levels and a greater chance of developing metabolic syndrome.
12 citations,
February 2022 in “International Journal of Clinical Practice” Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.
12 citations,
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
10 citations,
February 2007 in “Current Opinion in Endocrinology, Diabetes and Obesity” Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
8 citations,
April 2017 in “Medical Hypotheses” Men with early balding may have hormonal imbalances similar to women with PCOS and could benefit from similar treatments.
7 citations,
October 2012 in “S. Karger AG eBooks” Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.
7 citations,
January 1992 in “Adolescent and pediatric gynecology” Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.