26 citations
,
October 2020 in “Pediatric Dermatology” This study found that oral tofacitinib led to clinically significant improvement in alopecia areata severity scores among pre-adolescents, though results varied and further evaluation in clinical trials is needed.
26 citations
,
April 2019 in “Journal of Cosmetic Dermatology” This review discusses the potential of herbal treatments like Saw palmetto, Green tea, and Rosemary as alternatives to conventional drugs for androgenetic alopecia, noting that these herbs may inhibit the 5-alpha-reductase enzyme and reduce hair loss with fewer side effects.
26 citations
,
October 2017 in “Clinical Reviews in Allergy & Immunology” This review explores skin manifestations associated with autoimmune liver diseases and highlights known and probable links, such as vitiligo's strong association with autoimmune hepatitis.
26 citations
,
February 2002 in “Urologic clinics of North America” This review examines the placebo response in conditions such as allergies and weight loss, highlighting its significance in both conventional and alternative medicine randomized trials, without reporting any new results.
25 citations
,
April 2018 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections improved hair density and diameter in women with androgenetic alopecia not responding to other treatments over 24 weeks, with no adverse events reported.
25 citations
,
October 2015 in “Dermatology” This study observed that dapsone may be effective for treating pustular psoriasis, as four out of five patients showed improvement after previously failing other treatments.
25 citations
,
September 2014 in “Dermatologic Surgery” This study found that hair transplantation using round grafts improved hair growth in African American women with end-stage CCCA, showing no postoperative scarring in the donor or recipient areas.
25 citations
,
July 2013 in “Actas Dermo-Sifiliográficas” This review discusses consensus guidelines for the use of acitretin in psoriasis, highlighting its ongoing utility in both mono and combination therapies, despite not always being recognized in treatment guidelines.
24 citations
,
November 2023 in “NEWPORT INTERNATIONAL JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES” This article reviews the various short- and long-term side effects of antiretroviral therapy for HIV, highlighting issues like dyslipidemia and hypertension, but reports no new clinical results.
24 citations
,
February 2022 in “Reviews in Endocrine and Metabolic Disorders” This review reports that women with polycystic ovary syndrome are at 28%–50% higher risk of SARS-CoV-2 infection, with increased rates of COVID-19-related hospitalization, morbidity, and mortality.
24 citations
,
November 2015 in “Annals of Nutrition and Metabolism” This study found that specific SHBG gene variants and haplotypes are associated with polycystic ovary syndrome, suggesting that SHBG may be a candidate gene for the condition.
24 citations
,
June 2011 in “Andrologia” This study found that Ganoderma lucidum extracts reduced prostate enlargement and improved symptoms in testosterone-treated rats, suggesting potential benefits for managing benign prostatic hyperplasia.
23 citations
,
January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
23 citations
,
November 2007 in “Journal of cosmetic dermatology” This study concluded that both phosphatidylcholine alone and with organic silicium effectively reduced submental fat, achieving optimal results after three sessions with mild and temporary adverse effects.
23 citations
,
February 1979 in “Veterinary Clinics of North America: Small Animal Practice” This review discusses the physicochemical properties, binding mechanisms, and factors affecting corticosteroid-binding globulin (CBG) functions, but reports no new clinical results.
22 citations
,
January 2015 in “The Cochrane library” This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.
21 citations
,
July 2018 in “The Journal of Sexual Medicine” This article updates the process of care model for evaluating erectile dysfunction, emphasizing comprehensive evaluation and a combination of pharmacotherapy and counseling tailored to patient dynamics.
21 citations
,
July 2016 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have elevated cardiovascular risk markers, with levels being higher in obese participants compared to non-obese participants.
21 citations
,
November 2014 in “Journal of Endocrinological Investigation” This review discusses cross-sex hormone therapy for managing gender dysphoria in transsexual individuals and reports no new clinical results; it highlights the need for education and culturally sensitive training for healthcare professionals.
21 citations
,
July 2014 in “Clinics in Dermatology” This review examines the role of hormones in acne pathogenesis, the use of hormonal therapies for treatment, and the importance of contraceptive counseling during isotretinoin therapy, but reports no new clinical results.
20 citations
,
June 2019 in “Experimental Dermatology” This study identified 14 genes affected by copy number variants that may contribute to alopecia areata, including four genes notably involved in autophagy and chromatin remodeling.
20 citations
,
May 2018 in “The Journal of Urology” This study concluded that 5α-reductase inhibitors were associated with improved survival in men with bladder cancer, while α-blockers showed no effect.
20 citations
,
September 2005 in “Clinics in Dermatology” This review discusses the skin manifestations of metabolic diseases like diabetes and gout, emphasizing their role in diagnosis and monitoring, but it presents no new research findings.
19 citations
,
March 2018 in “Expert Opinion on Drug Safety” In this narrative review, the researchers reported that the overall safety profile of drugs used for treating spondyloarthritis is generally good, with serious adverse events being rare, but emphasized the need for rheumatologists to tailor treatments and closely monitor patients for potential adverse events.
18 citations
,
August 2012 in “Cutaneous and Ocular Toxicology” This study found that alopecia areata patients had increased insulin resistance compared to controls, suggesting a potential link between inflammation, stress axis activation, and insulin resistance in this population.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
17 citations
,
February 2018 in “Journal of Cosmetic and Laser Therapy” In this study, researchers administered eight sessions of intradermal injections containing growth factors into the scalp of 1000 patients, reporting a significant reduction in hair fall in 83% of participants and increased total hair count and shaft diameter, with promising tolerance and safety.
16 citations
,
May 2019 in “Hormone and Metabolic Research” This systematic review found insufficient evidence to support protective effects of selenium on polycystic ovary syndrome complications, despite some studies suggesting it may reduce insulin resistance and dyslipidemia.
16 citations
,
January 2013 in “Internal Medicine” This study found that premature hair whitening intensity is independently associated with increased carotid artery intima-media thickness, suggesting a link between hair whitening and cardiovascular risk.
16 citations
,
August 2011 in “Annals of Allergy Asthma & Immunology” This report describes a case of a 19-year-old woman experiencing severe recurrent angioedema with airway issues, leading to multiple emergency visits and unsuccessful treatment with typical steroid-sparing agents.