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      American Academy of Dermatology 44th Annual Meeting Highlights

      research American Academy of Dermatology

      August 1986 in “Journal of The American Academy of Dermatology”
      Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.
      Sudden Akathisia After a Ziprasidone Dose Reduction

      research Sudden Akathisia After a Ziprasidone Dose Reduction

      16 citations , March 2006 in “˜The œAmerican journal of psychiatry”
      This report describes five cases where sudden akathisia occurred in female patients with bipolar disorder after a ziprasidone dose reduction, emphasizing potential unexpected side effects of second-generation antipsychotics.
      Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions

      research Melatonin membrane receptors in peripheral tissues: Distribution and functions

      506 citations , January 2012 in “Molecular and Cellular Endocrinology”
      This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
      Melatonin in the Skin: Synthesis, Metabolism, and Functions

      research Melatonin in the skin: synthesis, metabolism and functions

      252 citations , January 2008 in “Trends in Endocrinology and Metabolism”
      This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.
      Is COVID-19 Gender-Sensitive?

      research Is COVID-19 Gender-sensitive?

      228 citations , January 2021 in “Journal of Neuroimmune Pharmacology”
      This review explores possible reasons for why male COVID-19 patients experience more severe symptoms and higher fatality rates than female patients but provides no new clinical results.
      On the Role of Melatonin in Skin Physiology and Pathology

      research On the Role of Melatonin in Skin Physiology and Pathology

      222 citations , January 2005 in “Endocrine journal”
      This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
      Melatonin

      research MELATONIN

      220 citations , August 1988 in “Clinical endocrinology”
      This review provides a comprehensive overview of melatonin's physiological roles, effects, and clinical implications, but it does not present new experimental findings.
      Wound Healing and the Use of Medicinal Plants

      research Wound Healing and the Use of Medicinal Plants

      170 citations , September 2019 in “Evidence-based Complementary and Alternative Medicine”
      This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
      The Human Tri-Peptide GHK and Tissue Remodeling

      research The human tri-peptide GHK and tissue remodeling

      165 citations , January 2008 in “Journal of biomaterials science. Polymer ed.”
      This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.
      The Pharmacology of Methotrexate

      research The pharmacology of methotrexate

      155 citations , August 1991 in “Journal of The American Academy of Dermatology”
      This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
      Tregs: Where We Are and What Comes Next?

      research Tregs: Where We Are and What Comes Next?

      130 citations , November 2017 in “Frontiers in Immunology”
      This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
      Finasteride

      research Finasteride

      125 citations , January 1999 in “Drugs”
      This study found that oral finasteride 1 mg/day promotes hair growth and prevents further hair loss in a significant proportion of men with male pattern hair loss over two years.
      Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes

      research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes

      112 citations , November 2023 in “Nano-Micro Letters”
      This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.
      Antioxidants in Dermatology

      research Antioxidants in dermatology

      86 citations , June 2017 in “Anais Brasileiros de Dermatologia”
      This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.
      Nanozymes Expanding the Boundaries of Biocatalysis

      research Nanozymes expanding the boundaries of biocatalysis

      85 citations , July 2025 in “Nature Communications”
      This review examines the evolving field of nanozymes, highlighting their unique properties and biocatalytic capabilities that challenge traditional concepts of biocatalysis, with implications for sustainable applications and potential roles in physiological processes and disease pathogenesis.
      Molecular Basis of Hair Cell Loss

      research Molecular basis of hair cell loss

      66 citations , February 2015 in “Cell & tissue research/Cell and tissue research”
      This review explores the mechanisms of hair cell death due to factors like noise, ototoxic drugs, and aging and reports no conclusive clinical results; ongoing research may eventually enable preventive treatments for hearing loss.
      Sulfation of Minoxidil by Liver Sulfotransferase

      research Sulfation of minoxidil by liver sulfotransferase

      66 citations , September 1982 in “Biochemical Pharmacology”
      This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.
      Finasteride in the Treatment of Androgenetic Alopecia

      research Finasteride in the treatment of alopecia

      62 citations , April 2004 in “Expert Opinion on Pharmacotherapy”
      This article reviews the use of finasteride for treating male pattern hair loss, highlighting its mechanism of action in reducing DHT and noting its safety profile with some common adverse effects.
      Acne

      research ACNE

      58 citations , January 1997 in “Dermatologic Clinics”
      This study found that daily consumption of soft drinks significantly increases the risk of moderate-to-severe acne in adolescents, particularly if sugar intake from these drinks exceeds 100 grams per day.