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      Minoxidil Use in Dermatology, Side Effects, and Recent Patents

      research Minoxidil Use in Dermatology, Side Effects and Recent Patents

      152 citations , April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery”
      This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
      An Update on Congenital Adrenal Hyperplasia

      research An Update of Congenital Adrenal Hyperplasia

      151 citations , December 2004 in “Annals of the New York Academy of Sciences”
      This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
      Ichthyosis

      research Ichthyosis

      147 citations , January 2003 in “American journal of clinical dermatology”
      This review discusses various forms of ichthyosis, including genetic and acquired types, detailing their characteristics, causes, and potential management strategies, but reports no new clinical results.
      Treatment of Hirsutism with the Pure Antiandrogen Flutamide

      research Treatment of hirsutism with the pure antiandrogen flutamide

      130 citations , September 1990 in “Journal of the American Academy of Dermatology”
      This study found that combining flutamide with an oral contraceptive significantly reduced hirsutism, acne, and seborrhea in patients after seven months, without significant side effects.
      Oxidative Stress in Aging of Hair

      research Oxidative stress in ageing of hair

      126 citations , January 2009 in “International Journal of Trichology”
      This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.
      TRP Channels in Skin Biology and Pathophysiology

      research TRP Channels in Skin Biology and Pathophysiology

      124 citations , December 2016 in “Pharmaceuticals”
      This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.
      Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes

      research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes

      112 citations , November 2023 in “Nano-Micro Letters”
      This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.
      Melatonin and the Hair Follicle

      research Melatonin and the hair follicle

      109 citations , October 2007 in “Journal of pineal research”
      This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.
      Baiting Proteins with C60

      research Baiting Proteins with C60

      106 citations , April 2010 in “ACS Nano”
      This study found that about 80% of known fullerene-binding proteins rank in the top 10% of scorers for C60 docking sites, confirming the accuracy of the predictive model used.
      Aging of Hair

      research Aging of hair

      99 citations , June 2005 in “Journal of Cosmetic Dermatology”
      This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.
      Nutraceuticals: A Review

      research Nutraceuticals: A Review

      95 citations , February 2018 in “Dermatology and Therapy”
      This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
      Pharmacokinetic Studies of Minoxidil

      research Pharmacokinetic studies of minoxidil

      90 citations , May 1972 in “Clinical Pharmacology & Therapeutics”
      Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
      Hormonal Contraceptives: Pharmacology Tailored to Women's Health

      research Hormonal contraceptives: pharmacology tailored to women's health

      88 citations , June 2016 in “Human Reproduction Update”
      This review discusses developments in oral contraceptives, highlighting improved individualization, reduced side effects, and enhanced suitability for various women's health needs, but it reports no new clinical results.
      Adverse Effects of Common Medications on Male Fertility

      research Adverse effects of common medications on male fertility

      77 citations , June 2015 in “Nature Reviews Urology”
      This article reviews the effects of various medications on male fertility, noting that while commonly used drugs can mostly have reversible impacts, conclusive human evidence remains limited.
      Skin Connective Tissue and Aging

      research Skin connective tissue and ageing

      77 citations , July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.
      Diagnosis of Hyperandrogenism: Biochemical Criteria

      research Diagnosis of hyperandrogenism: Biochemical criteria

      77 citations , June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism”
      This review discusses the importance of androgen production and metabolism in hyperandrogenism, the use of specific serum markers for diagnosis, and the need for improved assays for clinical testing, but reports no new results.
      Dienogest

      research Dienogest

      64 citations , January 1998 in “Drugs”
      In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.
      New Therapeutic Approach to the Hirsute Patient

      research New Therapeutic Approach to the Hirsute Patient

      60 citations , September 1979 in “Fertility and sterility”
      This study found that spironolactone reduced testosterone production and urinary 17-ketosteroid excretion, leading to a decrease in hair growth rate and a change in hair texture in women.
      The Impact of Oxidative Stress on Hair

      research The impact of oxidative stress on hair

      59 citations , November 2015 in “International Journal of Cosmetic Science”
      This review considers oxidative stress effects on hair aging and emphasizes the need for dermatologists to recognize and treat factors affecting scalp and hair health, but it provides no new clinical findings.
      Peripheral Androgens And The Role Of Androstanediol Glucuronide

      research 6 Peripheral androgens and the role of androstanediol glucuronide

      57 citations , May 1986 in “Clinics in endocrinology and metabolism”
      This review found that women with idiopathic hirsutism may have increased 5α-reductase activity, as indicated by elevated levels of a dihydrotestosterone-reduced metabolite, but more research is needed to confirm its clinical relevance as a biomarker.