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This review discusses how androgens may regulate wound healing and inflammation, noting that testosterone appears to inhibit healing and promote inflammation, but it reports no new clinical results.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.

This review discusses the pharmacologic properties, mechanisms, dosing options, and adverse effects of systemic glucocorticosteroids in dermatology, but reports no new findings.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

This study found that finasteride significantly improved hirsutism scores in women over 12 months and was well-tolerated with no serious side effects.

Minoxidil reduces lysine hydroxylase in skin cells.

This review discusses the potential of ozone therapy as an adjuvant to radio-chemotherapy for cancer patients, noting enhanced treatment effects and improved quality of life, but it presents no new research findings.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

This study found that millimolar concentrations of minoxidil in the skin induced VEGF production through HIF-1 stabilization by inhibiting PHD-2, implying a molecular mechanism for hair growth promotion.

This study found that minoxidil inhibited lens epithelial cell migration, proliferation, and collagen secretion in vitro, suggesting it may help prevent postoperative capsular opacification.

This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.

This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.

This study suggests that minoxidil is a potent stimulator of elastin expression in embryonic skin fibroblasts, primarily affecting elastin mRNA levels, without impacting cell proliferation during the stationary phase.

This study suggests that androstendione and DHEA are useful indicators for diagnosing hyperandrogenemia in hirsute women, while DHEAS was not found to be helpful.

This study observed that Cyp27b1−/− mice exhibited growth and skeletal abnormalities similar to those of Vdr−/− mice, despite differences like the development of alopecia in Vdr−/− mice, suggesting that 1α,25D3 may directly influence chondrocyte proliferation and differentiation.

Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.

This study suggests that the vitamin D receptor and hairless gene may directly regulate each other via a transcriptional mechanism, potentially explaining phenotypic similarities between atrichia and VDRRIIa rickets.

This review addresses clinical findings in parathyroid disease and discusses the metabolism of calcium, phosphorus, vitamin D, and parathyroid hormone, reporting no new results.

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

This review summarizes evidence suggesting that smoking is associated with alopecia and premature hair graying, with smokers showing higher prevalence than nonsmokers.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

This study found that biotransformation of finasteride by Aspergillus niger produced two metabolites with different levels of lipoxygenase inhibition, suggesting potential for developing more potent derivatives.

This review discusses melanocytes' role in pigmentation, their clinical significance in conditions like vitiligo and hair graying, and highlights current research on hair follicle regeneration without reporting new clinical results.

Hair graying may help prevent cancer by protecting stem cells.

This case report describes a 37-year-old female with non-classical congenital adrenal hyperplasia who presented with severe acne, progressive hair loss, and primary infertility, managed with prednisolone.

This study suggests that while vitamin D3 deficiency is linked to alopecia areata severity, evidence for the effectiveness of supplementation or topical calcipotriol treatment remains inconsistent and low quality.

In this study, methanol extracts from Thai-colored rice fermented with Aspergillus molds exhibited an increase in polyphenolic content and antioxidant activity, outperforming Thai white and Japanese white rice, notably transforming key polyphenols like quercetin and ferulic acid.

This study observed that 25-hydroxyvitamin D3 restored rickets symptoms in genetically modified rats, suggesting its direct action through vitamin D receptor pathways.