July 2025 in “Bulgarian Portal for Open Science” In this study, researchers explained that healing of extensive skin defects involves granulation filling the wound cavity, followed by epithelialization from skin edges and hair follicles, which are crucial steps in wound healing.
This scoping review found that microneedle patches loaded with exosomes, primarily derived from mesenchymal stem cells, show promising potential for delivering exosome therapies to treat non-cicatricial alopecia, suggesting new directions for enhancing hair follicle regeneration.
February 2025 in “Journal of Nutrients” This research reviews the scientific literature on bone broth extract, exploring its nutritional composition, potential health benefits, food industry applications, and risks such as heavy metal and antibiotic contamination. Results are not reported in this summary.
This study introduced a novel framework called SL-HyDE that significantly improved zero-shot dense retrieval accuracy in medical information retrieval without relying on labeled data.
January 2025 in “Journal of Materials Chemistry B”
December 2024 in “Journal of Clinical Medical Research” This study explores regenerative medicine's potential to improve quality of life, especially in aging populations, by examining key components like triggering agents, potentiators, and additives, and how their combined use may accelerate tissue repair through a strategy called stacking.
December 2024 in “Deleted Journal” This review explores the challenges of treating chronic wounds and highlights regenerative medicine as a promising approach, emphasizing the roles of growth factors, stem cell therapies, and novel regenerative treatments in improving wound healing and tissue regeneration.
November 2024 in “International Journal of Research and Review” This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.
June 2024 in “Frontiers in pharmacology” This study found that a 2-deoxy-D-ribose gel stimulated hair follicle growth in mice with androgenic alopecia, showing effects similar to minoxidil without additional benefits from combining the two treatments.
May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that hair with lower levels of keratin associated proteins reduced the foreign body response in mouse subcutaneous implant tests compared to hair with higher keratin levels.
January 2024 in “Clinical, cosmetic and investigational dermatology” This review suggests that dermatological cosmetic procedures can be safely performed on dark-complexioned skin with appropriate treatment adjustments, highlighting the need for careful consideration to prevent adverse effects.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
December 2023 in “Scientific reports” This study assessed three lactic acid bacteria-fermented proteins and found that F-WPI and F-SPI could normalize osteoclastogenesis markers in vitro, while F-SPI enhanced osteoblastogenesis markers, suggesting potential as dietary supplements for osteoporosis prevention, though further research into mechanisms is needed.
November 2023 in “Global journal of medical research” This study highlights the importance of understanding the rheological properties of hyaluronic acid fillers, including viscosity, cross-linking, and concentration, to optimize their use in addressing facial aging by maximizing clinical effects.
September 2023 in “Frontiers in bioengineering and biotechnology” This review explores the role of JAG1 in disease treatment, highlighting the need for effective methods to deliver JAG1 in its bound form to activate NOTCH signaling for therapeutic applications in craniofacial bone loss and myocardial infarction.
June 2023 in “Research Square (Research Square)” This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.
January 2023 in “Annali di stomatologia” This review traces the development and application of Platelet-rich Plasma in regenerative medicine, emphasizing its role in tissue healing and bone regeneration, but reports no new clinical results.
January 2023 in “Book of Abstracts” COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.
September 2022 in “Institutional Repositories DataBase (IRDB)” Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.
This study found that sericin dressing containing collagen hydrolysate significantly reduced wound healing time and improved scar quality compared to commercial dressing in split-thickness skin graft donor sites.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.
June 2019 in “The Egyptian Journal of Histology” In this study, hyaluronic acid filler injections in albino rats increased subcutaneous tissue thickness, collagen and elastic fibers, and vascularization, suggesting potential benefits for combating skin aging and defects.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.
January 2018 in “Springer eBooks” Men and women need different facial rejuvenation treatments due to distinct aging processes and anatomical differences.
January 2016 in “Journal of Materials Chemistry B” Advancements in biomaterials and nanotechnology are improving medical applications like hair growth, bone regeneration, and cancer treatment.
February 2015 in “Journal of Biomedical Materials Research Part B: Applied Biomaterials” This study suggests that 4-META resin may be more effective than cyanoacrylate for promoting wound healing in rats, as the wounds were covered by epithelial tissue faster with 4-META resin.
This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.
September 2011 in “Clinical Biochemistry” This study indicated that a novel calcium-phosphate nanoflower coating on titanium surfaces had high surface area, low cytotoxicity, and promising cell affinity, suggesting it could be a potential alternative modification method for titanium implants.