The authors of this study concluded that higher calcium levels in hair may indicate early metabolic changes leading to osteopenia or osteoporosis in menopausal women, even before detectable by standard DEXA imaging.
110 citations
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November 1984 in “The American Journal of Medicine” This study observed that children with a genetically transmitted defect in the 1,25-dihydroxyvitamin D3 receptor experienced spontaneous healing of rickets as they aged, despite persistent mineral imbalances during treatment.
135 citations
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December 2006 in “PLoS Medicine” This study suggests that intermediate-size hyaluronate fragments may enhance keratinocyte proliferation and improve skin thickness in atrophic conditions through a CD44-dependent mechanism.
December 2024 in “ACS Applied Materials & Interfaces” In this study, dynamic hyaluronic acid hydrogels with properties like injectability and controlled degradation were developed to enhance healing and remodeling of diabetic wounds, achieving effects such as inflammation reduction, increased angiogenesis, and neovascularization, leading to complete wound healing.
This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.
January 1980 in “中国科学A辑(英文版)” This study found that the molecular structures of α-keratin and collagen in a 2,100-year-old female cadaver's hair and tendon were preserved, while fibrous molecule aggregations were altered.
5 citations
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August 2011 in “Journal of Dermatological Science” In this study, researchers found that dentin sialoprotein and phosphophoryn are present in rat and mouse hair follicles, suggesting these proteins may play a role in hair follicle development, similar to their role in dentin mineralization.
22 citations
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January 1990 August 2025 in “Marine Drugs” This study evaluated a new composite material made from PLA, ALG, ZnS, and HT for blood-contacting applications, finding it improved surface characteristics and displayed anticoagulant properties and high biocompatibility with no genotoxic effects on blood and skin cells.
6 citations
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August 1989 in “European journal of pediatrics” This case study describes a child with rickets and alopecia who responded to a small dose of 1-a-hydroxyvitamin D3, but her alopecia remained unchanged despite treatment.
October 2025 in “Nephrology Dialysis Transplantation” In this case report, a young woman experienced acute kidney injury linked to the use of a hair straightening product containing glyoxylic acid, suggesting dermal absorption may lead to calcium oxalate nephropathy; this highlights the need for regulatory review and public health intervention.
11 citations
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December 2018 in “Bone” This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.
17 citations
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January 2023 in “Frontiers in Bioengineering and Biotechnology” This study reported that newly developed quaternary ammonium chitosan/carboxymethyl starch/alginate sponges effectively inhibit bacterial growth and promote rapid hemostasis in wound management after tooth extraction in animal models, showing significant promise for clinical use in preventing complications like dry socket.
252 citations
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January 1991 in “Electron Microscopy Reviews” February 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, all-trans retinoic acid was found to protect against oxidative stress-induced apoptosis in cultured hair cell-like cells.
1 citations
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June 2000 in “PubMed” This study observed that osteopontin mRNA levels in rat hair follicles vary throughout the hair cycle, peaking during the catagen phase and disappearing in the telogen and anagen phases.
15 citations
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January 1971 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study indicates that hair analyses for calcium and phosphorus are unlikely to be useful for assessing the nutritional status of horses, suggesting soil and feed analyses as more effective alternatives.
14 citations
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November 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that platelet-rich plasma injections were more effective than hyaluronic acid in improving survival rates, reducing re-intervention, and enhancing patient satisfaction for mid-term knee osteoarthritis treatment.
3 citations
,
December 2010 in “Annals of tropical paediatrics” In this study, the authors reported that while conventional treatment improved rickets in a boy with vitamin D-dependent rickets type II, it also resulted in unexpected improvement in his alopecia.
January 2000 in “Zhongguo yixue wulixue zazhi” This study observed that human hair keratin showed distinct morphological features depending on the dissolution speed, which could have potential applications in clinical settings for developing self-tendons.
24 citations
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June 2021 in “Annals of Translational Medicine” This review discusses the potential of human placental extract (HPE) in cartilage regenerative medicine for osteoarthritis, noting its significant anti-inflammatory and regenerative properties observed in vitro and in vivo studies, but reports no new clinical results.
5 citations
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October 2002 in “PubMed” In this study, the degradation of HHK scaffold particles was linked to the activation and proliferation of satellite cells, which may contribute to new muscle fiber formation.
3 citations
,
January 2023 in “Journal of Hard Tissue Biology” This study found that Wnt10a expression in odontoblasts increased with dental pulp regeneration and may be a potential non-cellular agent for inducing dental pulp regeneration with dentine-inducing capacity.
23 citations
,
September 2018 in “Journal of Investigative Dermatology” This study reported that treating wounds with a hydrogel from acellular porcine adipose tissue and adipose-derived stem cells may significantly enhance wound healing and regeneration by promoting new adipocyte formation.
12 citations
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October 2015 in “Journal of bioactive and compatible polymers” This study found that keratin hydrogels extracted from human hair showed potential as biodegradable and biocompatible filler materials, promoting angiogenesis and cell proliferation in rat models.
January 2024 in “Wiadomości Lekarskie” This case study reports that bisphosphonate therapy, used to treat osteoporosis, can lead to jawbone necrosis, as demonstrated in an 82-year-old patient who experienced severe complications requiring surgical intervention. The authors recommend comprehensive dental care before and avoidance of invasive procedures during bisphosphonate treatment.
January 2024 in “Research Square (Research Square)” This study reports that adjusting the valence states of Mo in Pluronic F127-coated MoO3-x nanozymes enhances their selective H2O2-related catalytic activity, showing promise in acute kidney injury treatment and enabling real-time monitoring of therapy effectiveness through ROS-responsive photoacoustic imaging.
20 citations
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February 2017 in “European journal of pharmaceutical sciences” This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.
1 citations
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October 2017 in “Frontiers in Physiology” This article proposes a hypothesis that KRT75, a protein found in hair follicles, was evolutionarily co-opted by ameloblasts during the development of prismatic enamel in synapsids, but reports no new results.
478 citations
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September 1996 in “Proceedings of the National Academy of Sciences” This study found that overexpression of PTHrP in mice chondrocytes led to short-limbed dwarfism and delays in endochondral ossification, highlighting PTHrP's role in inhibiting chondrocyte differentiation.