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This study investigated chitosan–hydroxyapatite biocomposites, finding them to enhance anti-inflammatory cytokine expression, support cellular activities, and reduce pro-inflammatory cytokines in a dermatitis model, while highlighting gaps in understanding their immune modulation and issues with reproducibility for clinical use.

This review found limited but suggestive evidence that Calcium Hydroxylapatite may promote skin regeneration through increased collagen production, cell proliferation, and angiogenesis, although most studies had methodological limitations.

In this report, researchers observed that a single treatment using a combination of hyperdiluted calcium hydroxylapatite, platelet-rich plasma, and hyaluronidase improved neck wrinkles and skin laxity in two patients, indicating preliminary evidence for the safety and efficacy of this novel therapy.

This study observed that calcium hydroxylapatite can be successfully incorporated and retained in the dermis for at least six weeks after fractional laser treatment, with new collagen forming around it.

In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.

This research developed a zinc-doped nanocomposite using biodegradable materials, observing effective bone targeting and regeneration capabilities in vivo, with no observed cytotoxicity in the MG63 cell line, potentially due to blocking Farnesyl Diphosphate Synthetase to inhibit osteoclastic activity and promote osteogenesis.

This study found that experimentally induced calcification in rat skin led to rapid and localized mineralization in hair follicles, progressing to more extensive calcification with prior hypercalcemic treatment.

This study found that dutasteride affected spinal bone formation in curdlan-treated SKG mice, while DHT treatment reduced osteoblast differentiation in vitro, suggesting that DHT inhibition might unexpectedly increase spinal ankylosis progression in ankylosing spondylitis patients.

This study found that hair follicle tissue effectively induced mineral formation in calcium phosphate solutions, likely due to its nucleating ability, which was lost when the tissue was lyophilized and stored.

This study reports that multifunctional electrospun scaffolds containing silver vanadate, hydroxyapatite, and graphene oxide significantly improved wound healing in a rat model, promoting rapid re-epithelialization, enhanced mechanical properties, and strong antibacterial activity, making them promising candidates for advanced wound care applications.

This article discusses the use of platelet concentrates in regenerative surgeries for periodontal and bone defects but presents no new clinical results, emphasizing their potential benefits over traditional methods.

This article series reviews volumetric restoration techniques for different facial regions by expert authors, offering assessments of specific products but provides no new clinical results.

This study found that AI using YOLOv11 architecture can reliably differentiate between hyaluronic acid and silicone oil cosmetic fillers on ultrasound, achieving high accuracy, whereas identifying calcium hydroxyapatite and polymethylmethacrylate remains less consistent, requiring further improvements.

This narrative review examines advancements in regenerative aesthetic medicine, focusing on injectable modalities like PRP, polynucleotides, and exosomes, but highlights the need for more robust evidence and standardization in clinical applications.

This review highlights that injectable biostimulatory agents like poly-L-lactic acid, polycaprolactone, and calcium hydroxyapatite are effective in regenerative aesthetics by enhancing collagen production, stimulating adipogenesis, and improving dermal quality, although further research is needed to standardize protocols and confirm long-term safety and efficacy.

This study observed that infrared light therapy, alone or combined with hyaluronic acid and calcium hydroxylapatite, effectively improved skin laxity with high patient satisfaction and minimal adverse effects among women aged 37 to 68.

This article reviews methods for temple region rejuvenation and reports no new clinical results; the authors emphasize the importance of understanding temple anatomy for optimal aesthetic outcomes.

Nonsurgical facial treatments are becoming more popular due to their natural-looking results and minimal invasiveness.

In this chapter, the authors explore hyperdiluted CaHA as a new potential treatment for mild to moderate hair loss, providing preliminary insights into its application as an innovative option within regenerative therapies.

This study reviewed cases of filler-induced alopecia and found that hyaluronic acid injections were most commonly associated with this condition, highlighting that hyaluronidase treatments can rapidly restore hair density, while alternative interventions need further exploration.

This source provides informal summaries and case reports on potential complications in hair restoration surgery, with no specific outcomes reported in the abstract.

This study suggests that although hydroxyapatite gel has strong bactericidal effects, its combination with platelet-enriched blood autoplasm does not enhance antibacterial activity in endodontic treatment for chronic apical periodontitis.

This article reviews the latest data on non-invasive body rejuvenation techniques, discussing advancements in filler technology and offering insights into their effectiveness and safety for both practitioners and patients interested in non-surgical procedures.

This study found that a bioactive borosilicate glass containing Sr and Cu ions exhibited promising mechanical strength, biocompatibility, and antibacterial activity, particularly the CuSr-1 wt.% composition, suggesting potential for use in orthopedic implants and bone tissue engineering.

This review article highlighted the diverse applications of functionalized materials from bacterial cellulose, detailing advances in both in situ and ex situ methods for enhancing these materials' properties, particularly for medical applications, and proposed directions for future research.

This study provides a comprehensive review of the use of electrospinning technology to create 3D porous structures for bone implants, emphasizing the synergy between biomedicine and materials science necessary for developing orthopedic materials.

This study reports that reconstructing perioral soft tissue defects with submental tissue resulted in satisfactory aesthetic outcomes and minimal donor-site morbidity.

This study reports the purification of a specific sulphotransferase from rat liver that catalyzes the sulphation of minoxidil, potentially implicating it in minoxidil's bioactivation.

This case report describes a successful frontal region reconstruction using Cerament for a 50-year-old man, resulting in satisfactory forehead morphology and improved appearance four years post-surgery.