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New compounds were made that effectively block a specific enzyme related to androgen conditions.

New compounds with carborane showed anti-androgen effects similar to flutamide.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

Histone modification is key in treating chronic inflammatory skin diseases.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

PDF2 senses specific lipids and regulates root growth and gene expression in Arabidopsis.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

Adding a second method to PROTACs could improve cancer treatment.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.

The transporter protein SH1446 in Staphylococcus hominis is key to underarm odor production.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.