3 citations,
August 2022 in “Pharmaceuticals” Solidified SEDDS improve drug stability and bioavailability better than liquid SEDDS.
2 citations,
May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
1 citations,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
March 2024 in “International journal of nanomedicine” Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
October 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
4 citations,
August 2023 in “Materials” New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.
3 citations,
December 2022 in “Cells” Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
522 citations,
January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
11 citations,
August 2011 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
61 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.
January 2015 in “Elsevier eBooks” Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
151 citations,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
141 citations,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
62 citations,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
58 citations,
April 1998 in “Journal of biological chemistry/The Journal of biological chemistry” CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
39 citations,
August 2017 in “Colloids and Surfaces B: Biointerfaces” 50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
30 citations,
October 2015 in “Journal of Ethnopharmacology” Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
22 citations,
November 2018 in “Brazilian Journal of Pharmaceutical Sciences” New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
20 citations,
September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
16 citations,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
14 citations,
January 2016 in “Elsevier eBooks” Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
3 citations,
October 2014 in “Pharmaceutical Development and Technology” The study found a way to improve a skin-applied minoxidil formula using a specific design method.
February 2024 in “Pharmaceutical research” Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.
January 2023 in “Postępy Dermatologii i Alergologii” Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
431 citations,
October 2008 in “Current Medicinal Chemistry” Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
263 citations,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” Polymeric nanoparticles show promise for treating skin diseases.
153 citations,
November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.