Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.

This study developed a degradable and bioactive citrate-based polyurethane adhesive that achieves rapid and strong tissue adhesion, exhibiting improved bonding strength in wet environments, biocompatibility, biodegradability, and hemostatic properties, with potential to enhance wound healing by promoting angiogenesis.

The researchers reported that pulsed FUS can enhance the tumor-killing effects of cisplatin by unbinding it from albumin in cervical cancer, but further study is needed to measure its selective delivery to tumors.

This study used quantitative methods to identify new geometric and mechanical parameters of curly and kinky/coily hair, aiming to improve classification and develop better personal care products for these hair types.

This study identified two distinct fibroblast subsets in mouse skin, revealing that adult skin scarring occurs due to the repair process utilizing only one, lineage-restricted fibroblast type instead of coordinated diverse populations.

Dr. Jia-You Fang is a highly experienced researcher in drug delivery and related fields, with numerous publications and international collaborations.

In this study, researchers developed and tested hair gels using pectin from mango and coconut oil as a potential natural treatment for traction alopecia in black women, reporting stability in some formulations and rheological properties that may support their use in innovative phytocosmetics.

In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.

This study identified new geometric and mechanical parameters for curly and kinky/coily hair, which may inform more effective personal care products tailored to these hair types.

In this animal study, the researchers found that DPP4 plays a crucial role in scar formation and wound-induced hair follicle neogenesis in mice, impacting regenerative repair.

This study found that the protein p63 requires morphogenetic signals to regulate gene expression effectively during skin cell differentiation, highlighting its complex role in therapeutic reprogramming for conditions like epidermolysis bullosa.

This study demonstrates that pH-responsive nanogels designed with comb-like anionic polymers significantly improved oral delivery of the chemotherapy drug camptothecin, enhancing drug stability in acidic conditions and release in the intestines, with increased cellular uptake and cytotoxic effects against colorectal carcinoma cells.

This study suggests that Vigilon®, a new occlusive wound dressing with high water content, may promote better wound healing than other similar dressings in dermatologic surgery.

In this study, researchers developed thermoresponsive nanogels that effectively penetrate hair follicles and release a model drug when triggered by temperature, demonstrating greater penetration for medium to large nanogels (300–500 nm) compared to smaller ones.

In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.

This review examined natural hair gels, incorporating an experimental polyherbal gel, and reported that these formulations possess multifunctional benefits for hair health, while also highlighting the importance of product safety and potential for innovative delivery systems.

In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.

In this double-blind study, a novel hyaluronic acid gel for lip augmentation was found to be as effective and safe as a commercially available gel, with similar adverse event profiles and high patient and investigator improvement ratings over six months.

This study suggests that combining LMWHA solution and HCO might improve mild to moderate urinary incontinence in women with GSM, potentially offering benefits over HA therapy alone, but further research is needed.

This article updates a prior work on pharmacophore modeling and highlights the advances in 3D database searching technologies for drug design, without presenting new research findings.

In this study, mycorrhizal fungal inoculation was associated with increased root-hair growth and enhanced drought tolerance in trifoliate orange by modulating auxin synthesis and transport under water stress conditions.

This review examines the dermatologic effects of tobacco use and nicotine, noting potential benefits and drawbacks for various skin conditions, but reports no new clinical results.

This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.

This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.

This study found that drug delivery through human scalp skin may be more effective for lipophilic and hydrophilic drugs compared to abdominal skin, highlighting the potential of intrafollicular delivery methods.

This study found that cultured human dermal papilla cells formed into three-dimensional spheres have an increased ability to induce hair follicles from mouse epidermal cells compared to two-dimensional cultures.

This study found that liposomes coated with cationic polymers, chitosan and Eudragit EPO, showed improved physicochemical stability and enhanced skin diffusion of aciclovir and minoxidil compared to uncoated liposomes.

This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.

This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.

This study found that finasteride competitively inhibits the enzyme AKR1D1 with low micromolar affinity but does not act as a mechanism-based inactivator.