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Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.

A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.

Hair follicles help magnesium get through the skin more effectively.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Scalp skin barrier affects hair loss; personalized treatments needed.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

IPM enhances skin penetration of hydrophilic drugs.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.

ACBP is crucial for healthy skin in mice.

Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.

Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.

An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.