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Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Gene differences may affect baldness treatment response in Korean men.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Finasteride potentially treats hair loss by reducing DHT production.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Certain drugs that block specific enzymes can help treat prostate diseases.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Testosterone's muscle-building effects do not require its conversion to DHT.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.