7 citations,
January 2009 in “Experimental Dermatology” The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
249 citations,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
82 citations,
August 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
46 citations,
December 1992 in “Journal of Investigative Dermatology” Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.
44 citations,
April 2003 in “European journal of pharmaceutical sciences” Lipophilic dyes accumulate more in hair follicles when delivered with surfactant-propylene glycol solutions.
27 citations,
November 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
17 citations,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
5 citations,
May 2020 in “Pharmaceutical Research” Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
1 citations,
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Fetal skin has unique immune cells different from adult skin.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
17 citations,
October 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
1 citations,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
6 citations,
September 2019 in “Skin pharmacology and physiology” RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.
19 citations,
January 1987 in “Dermatology” Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
54 citations,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
10 citations,
July 2013 in “British Journal of Dermatology” Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.
16 citations,
June 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
196 citations,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
46 citations,
September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
66 citations,
August 2001 in “Experimental Dermatology” Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
9 citations,
September 2018 in “Journal of Photochemistry and Photobiology B-biology” A hair-growth formula with cystine and thiamin helps protect skin cells against UV damage and improves their growth.
4 citations,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.
2 citations,
January 2017 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
165 citations,
January 2008 in “Journal of biomaterials science. Polymer ed.” The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
27 citations,
October 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.