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PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Albert M. Kligman, who turned 90 on March 17, 2006, made significant contributions to dermatology, including creating treatments for acne and studying skin aging.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Greasy hair spreads sebum twice as much as nongreasy hair over time.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

New acne treatments show promise as alternatives to traditional therapies.

Dandruff and seborrheic dermatitis are caused by yeast feeding on scalp oils, leading to irritation and flaking.

Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.

SCD1 inhibitors can cause skin issues in rodents.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

Fish oil improves skin health in people with diabetes and high cholesterol.

Most patients with anal Pemphigus Vulgaris had repeated episodes but fully recovered with treatment, without long-term problems.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.