130 citations,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
120 citations,
October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
72 citations,
October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
71 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
70 citations,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
47 citations,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
96 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
83 citations,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
58 citations,
October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
43 citations,
November 2013 in “Journal of Investigative Dermatology” Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.
5 citations,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
10 citations,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
2 citations,
September 2002 in “Dermatologic Surgery” Each group of hair follicles on the scalp shares one muscle that helps control hair movement.
64 citations,
July 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
24 citations,
September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
April 2018 in “Journal of Investigative Dermatology” Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.
April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
61 citations,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
6 citations,
February 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.
21 citations,
April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
51 citations,
February 2006 in “Clinics in Dermatology” Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.
33 citations,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
26 citations,
March 2014 in “International journal of pharmaceutics” Researchers created a skin treatment that could effectively deliver medication into hair follicles.
14 citations,
February 2021 in “International Journal of Pharmaceutics” Deer antler velvet serum helps hair grow and is safe for skin.
93 citations,
April 2012 in “International Journal of Cosmetic Science” Improving skin barrier and using antifungal treatments can help manage dandruff.
4 citations,
August 2005 in “Archives of Dermatological Research” Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.
January 2017 in “Springer eBooks” The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.