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In this study, human scalp hair grafted onto nude mice accurately reflected methyl mercury exposure, demonstrating its potential as a research model for monitoring mercury incorporation into human hair.

This study observes that TYK2 inhibition with BMS-986202 may extend hair follicle growth phases and decrease inflammatory cell markers in alopecia areata, suggesting potential for clinical application.

γδT cells can protect hair follicles from alopecia areata and promote hair regrowth.

This study used a 3D simulation to show that human hair provides varying levels of UV protection depending on head orientation and hair alignment, highlighting hair's role in scalp UV protection, especially for those with alopecia.

This study observed that human anagen hair follicles can grow in vitro when maintained serum-free, with possible implications for understanding hair follicle growth mechanisms.

This study found that intermediate hair follicles respond to testosterone by growing, but do not respond to finasteride, suggesting they may provide a novel and clinically relevant model for hair growth research.

This study developed a humanized scalp model in mice which demonstrated that transplanted cultured human hair follicle dermal cells contributed to the restoration of damaged hair follicles.

This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.

This study found that patients with androgenetic alopecia had increased scalp microbial diversity and reduced Staphylococcus abundance, particularly in the frontal and vertex regions, suggesting this dysbiosis as a sensitive indicator of AGA.

This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.

This study demonstrated that injecting reconstructed dermal papilla-like tissues in mice led to new hair growth, suggesting potential future applications in hair transplantation and baldness treatment.

This paper discusses two preclinical models for studying alopecia areata and finds that testing new therapeutic agents should involve both the C3H/HeJ mouse model and the humanized mouse model for comprehensive insights.

This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.

This study found that human scalp hair follicles transplanted onto chemotherapy-treated immunodeficient mice closely mimic chemotherapy-induced hair loss seen in cancer patients, providing a valuable model for research.

This study established a model using nude mice to successfully graft human scalp skin, maintaining hair follicle growth and skin integrity for at least two months, which may aid preclinical research.

This study demonstrated that several botanical extracts possess antioxidant properties, reducing oxidative stress and lipid oxidation in scalp treatments, with rosemary extract showing potential to improve scalp condition in a 4-week consumer trial.

This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.

Mesenchymal cells can significantly boost human hair growth and longevity.

This study found that a laboratory model using nude mice can produce human hair follicles with amino acid compositions resembling both normal and trichothiodystrophy-affected human scalp hair over extended periods.

This article argues that human scalp hair follicles could serve as a surrogate model for studying immune privilege in the human eye, offering a novel approach for ocular IP research.

This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.

In this study, researchers found that WNT activation influenced FGF expression in human scalp-derived fibroblasts, with mouse model results showing FGF9 increased hair follicle number and diameter, while FGF7 reduced diameter.

This study found that γδTregs significantly reduced autoimmune effects in humanized alopecia areata models, suggesting their potential as a novel cell-based therapeutic approach for managing the condition.

This study found that autologous Foxp3+ γδTregs, when tested in human scalp hair follicle models and mouse xenotransplants, can both prevent and treat alopecia areata by reducing immune privilege collapse and lymphocytic infiltration, suggesting their potential as a novel cell-based therapy for the disease.

This study reports the creation of a human dermal mesenchymal-like stem cell line from an androgenetic alopecia patient, which may serve as an in vitro model to explore alopecia mechanisms.

This pilot study suggests that topical cyclosporin may delay hair shedding and potentially treat alopecia, based on observations in a human scalp skin graft model on mice.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

This study found that autologous γdTregs displayed significant protective effects on alopecia areata-affected human scalp hair follicles in both ex vivo and in vivo settings, suggesting potential for future cell-based therapy.

In this study, γδTregs showed potential as a cell-based therapy for alopecia areata by preventing hair loss and promoting hair regrowth in humanized AA models.

This study found that autophagy plays a novel role in human hair growth, with altered autophagic flux during hair development phases influencing hair follicle behavior in a preclinical model.