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Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Hormones control reproduction and are crucial for body balance.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

WNT10B is linked to cancer development and affects survival and disease progression in various cancers.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.