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Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Spironolactone treatment increases the amount of testosterone available in the body.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Cell aging can be both good and bad for tissue repair.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

A3B5 can reduce skin pigmentation and slow melanoma growth.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Pumpkin seed oil may help hair grow and could be an alternative treatment for male hair loss.

Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.

Lipids from Schizochytrium sp. help prevent hair loss by protecting hair cells from damage and promoting hair growth.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.