research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
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research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Functional Hair Follicle Regeneration
Scientists made working hair follicles using stem cells, helping future hair loss treatments.
research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice
Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
research Tissue Homeostasis and Regeneration: Human Limitations and Potential
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Mechanical Force Drives the Initial Mesenchymal-Epithelial Interaction During Skin Organoid Development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Recent Advances in Exosomal Non-Coding RNA-Based Therapeutic Approaches for Photoaging
New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Functional Salivary Gland Regeneration by Transplantation of a Bioengineered Organ Germ
Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
research Metabolic Syndrome and Skin Diseases
Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.
research Dermal Papilla Cells: From Basic Research to Translational Applications
Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
research At the Dawn of Hair Research – Testing the Limits of Hair Follicle Regeneration
Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth
Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
research Small Molecules and Small Molecule Drugs in Regenerative Medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research In Vitro Hair Follicle Growth Model for Drug Testing
Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research The Pathogenesis and Treatment Progress of Androgenic Alopecia
Future treatments for androgenic alopecia may focus on reactivating hair follicle stem cells and improving drug delivery.
research Extracellular Vesicles for Cosmetic Applications
Tiny particles called extracellular vesicles show potential for improving skin health in cosmetics, but more research is needed to confirm their safety and effectiveness.
research The Dermal Papilla and Hair Follicle Regeneration: Engineering Strategies to Improve Dermal Papilla Inductivity
Improving dermal papilla cells can help regenerate hair follicles.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Wnt and Notch Signaling Pathway Involved in Wound Healing by Targeting c-Myc and Hes1 Separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research Opening New Horizons in Regenerative Dermatology Using Platelet-Based Autologous Therapies
Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
research Autologous Adipose Transplantation: An Effective Method to Treat Alopecia After Trauma - A Case Report
Using a patient's own fat tissue helped treat hair loss caused by an injury.
research Functional Ectodermal Organ Regeneration as the Next Generation of Organ Replacement Therapy
The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
research Experimental Studies of Glycine Max Merr. (Black Bean), Triticum Aestivum L. (Wheat) and Oryza Sativa L. (Rice Bran) Extracts on the Effects of Hair Growth Activity and Physical Properties
Black bean, wheat, and rice bran extracts can boost hair growth and improve hair quality.
research Androgenetic Alopecia: Therapy Update
There are many treatments for common hair loss, but more trials are needed to decide which are best.