research Human Skin Color: Origin, Variation, and Significance
Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
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research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study
Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
research Exploring the Potential Effect and Mechanisms of Protocatechuic Acid on Human Hair Follicle Melanocytes
Protocatechuic acid can reduce melanin production and boost antioxidant activity in hair follicles.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research A New Scalp Treatment for Anti-Aging Hair
The new scalp treatment preserves hair color, reduces hair loss, and maintains hair strength.
research N02. Hair and Nails
Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.
research Melan-A Positive Cells Significantly Expressed in Immune-Targeted Follicles of Alopecia Areata
Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
research Expression and Tissue Distribution Analysis of Angiotensin II in Sheep Skins Associated with White and Black Coat Colors
Angiotensin II is found at higher levels in black sheep skin and may influence coat color.
research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research The Multiple Uses of Azelaic Acid in Dermatology: Mechanism of Action, Preparations, and Potential Therapeutic Applications
Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research A Rare Repigmentation Pattern in a Vitiligo Patient: A Clue to an Epidermal Stem-Cell Reservoir of Melanocytes?
Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles
Caffeine may help reduce stress-induced hair loss.
research The Involvement of Androgens in Human Hair Growth
Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
research Classification of Surgical Therapies in Vitiligo
Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.
research Sox2 in the Dermal Papilla Regulates Hair Follicle Pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.
research Investigation Into the Role of HIF-1A Stabilization in Hair Follicle Metabolism
Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
research Clinical Pathobiology of Radiotherapy-Induced Alopecia: A Guide Toward More Effective Prevention and Hair Follicle Repair
The conclusion suggests that focusing on certain cellular pathways may improve the prevention and repair of hair loss caused by radiotherapy.
research Hair Follicular Cell/Organ Culture in Tissue Engineering and Regenerative Medicine
Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
research Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research A Review of the Etiologies, Clinical Characteristics, and Treatment of Canities
Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
research Phase I/IIa Clinical Trial for the Treatment of Androgenetic Alopecia Using Intradermal Injections of Cultured Autologous Dermal Sheath Cup Cells
Injections of special skin cells showed potential in treating hair loss, with some participants experiencing increased hair density.
research Thermal Imaging and Trichoscopy for Detecting Inflammation in Frontal Fibrosing Alopecia
Thermal imaging is a useful non-invasive method to diagnose active inflammation in frontal fibrosing alopecia.
research Backhousia Citriodora Leaf Extract: A New Active Solution to Control Hyper-Seborrhea for Multi-Ethnic Skins
Backhousia citriodora leaf extract effectively reduces oily skin across different ethnic groups.
research Stem Cells of the Hair Follicular Tissue: Application in Cell-Based Therapy for Vitiligo
Hair follicle stem cells could be used to treat the skin condition vitiligo.
research 282 Withdrawn
HIF-1A may aid hair growth, Backhousia citriodora improves skin, autologous cells stabilize hair loss, infrared thermography assesses alopecia, and a new treatment preserves hair.