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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Krt16-deficient mice help understand skin disorders like PC and FNEPPK.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Mutations in the P2RY5 gene cause autosomal recessive woolly hair.

Hair growth and development are controlled by specific signaling pathways.

Trichohyalin is a protein in hair follicles that helps form hair filaments.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Different body areas in mice produce different hair types due to interactions between skin layers.

Special cell particles from macrophages can help hair grow.

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.

Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.

The KRTAP21-1 gene affects wool yield and can help improve wool production.

Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.

Juglone from walnut extracts may help repair damaged hair.

Two mouse mutants have defective hair cuticle cross-linking.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.

Common variants in the Trichohyalin gene are linked to straight hair in Europeans.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Cyclosporine starts hair growth faster, while minoxidil makes it last longer.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.

Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.

Found new possible treatments for hair loss.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.