research Analysis of DNA in Hair Fibers
Small amounts of DNA can be found in the hair shaft, especially near the root, but it decreases with hair treatments and washing.
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research Concise Review: Human Dermis as an Autologous Source of Stem Cells for Tissue Engineering and Regenerative Medicine
Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
research Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells
Fat tissue stem cells may help increase hair growth.
research Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative Stress and Regulating Glycogen Breakdown in Human Hair Follicles
A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research A Cell-Based System for Screening Hair Growth-Promoting Agents
Apigenin may help promote hair growth and could treat hair loss.
research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein
Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
research Epidermal-Dermal Coupled Spheroids Are Important for Tissue Pattern Regeneration in Reconstituted Skin Explant Cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells
PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells
An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
research Human Scalp Hair: Modulation by Various Factors and Hormones - Do Estrogens Inhibit or Stimulate? A Perplexing Perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research Methods for Quantifying Intrafollicular Drug Delivery: A Critical Appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors
Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
research Hair Growth Potential of Salvia Plebeia Extract and Its Associated Mechanisms
Salvia plebeia extract can stimulate hair growth.
research Human Pollution Exposure Correlates With Accelerated Ultrastructural Degradation of Hair Fibers
Pollution exposure speeds up hair damage.
research Reversal of the Hair Loss Phenotype by Modulating the Estradiol-ANGPT2 Axis in the Mouse Model of Female Pattern Hair Loss
Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.
research Skin and Hair: Models for Exploring Organ Regeneration
Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
research Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells
Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
research The Human Type II Keratin Gene Cluster on Chromosome 12q13.13: Final Count or Hidden Secrets?
The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Dermal Papilla Cells Induce Keratinocyte Tubulogenesis in Culture
Skin cells can help create early hair-like structures in lab cultures.
research Ginsenoside Rg4 Enhances the Inductive Effects of Human Dermal Papilla Spheres on Hair Growth Via the AKT/GSK-3β/β-Catenin Signaling Pathway
Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.
research Androgenic Effect of Testosterone and Its Metabolites in Relation to Their Biotransformation in the Skin
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research Exploring the Potential of the Novel IFNγ Aptamer TAGX-0003 as a Treatment for Alopecia Areata in Pre-Clinical Models
The new aptamer TAGX-0003 shows promise as an effective treatment for hair loss disorder alopecia areata.
research Current Understanding and Treatment of Sex Hormone-Related Hair Diseases
Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
research Hair Growth-Promoting Effects of Astragalus Sinicus Extracts in Human Follicle Dermal Papilla Cells
Astragalus sinicus extracts may help promote hair growth and treat hair loss.
research Restoration of Follicular β-Catenin Signaling by Mesenchymal Stem Cells Promotes Hair Growth in Mice with Androgenetic Alopecia
Stem cells from umbilical cords can help regrow hair in mice with hair loss.
research Germacrene Analogs Are Anti-Androgenic on Androgen-Dependent Cells
Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.