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Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Genetic defects and UV radiation cause skin damage and aging.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

The 3D skin model is better for hair growth research and testing treatments.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Researchers found 15 new genetic links to skin traits in Japanese women.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Gray hair can potentially be reversed, leading to new treatments.

Stem cells could improve hair growth and new treatments for baldness are being researched.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

CD98hc's role in skin health decreases with age.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Genomic approach finds new possible treatments for hair loss.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

The engineered skin substitute helped grow skin with hair on mice.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.