Search

everythinglearnresearchcommunity

for

Search:↓

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Different body parts have varying levels of certain hair follicle markers.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Lower SMAD2/3 activation predicts more severe skin cancer.

The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

A man experienced hair loss from radiotherapy, which can be temporary or permanent depending on radiation dose, with potential treatments available.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Curcumin may help reverse aging by targeting specific genes.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.

The meeting highlighted the genetic basis of female pattern hair loss and various skin health insights.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.