research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
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research Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss
Using platelet-rich plasma, which is full of growth factors, can help treat pattern hair loss.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in Alzheimer's Disease and Rosacea
Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
research Advanced Polymer Hydrogels That Promote Diabetic Ulcer Healing: Mechanisms, Classifications, and Medical Applications
Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
research Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature
Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
research Identification of Hepatic Molecular Mechanisms of Action of Alpha-Tocopherol Using Global Gene Expression Profile Analysis in Rats
Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
research Perilla Frutescens: A Rich Source of Pharmacologically Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Topical Treatment for Scarring and Non-Scarring Alopecia: An Overview of the Current Evidence
Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.
research A Comparative Study of Therapeutic Response to Intralesional Injections of Platelet-Rich Plasma Versus Triamcinolone Acetonide in Alopecia Areata
PRP works faster and is a safe alternative to steroids for treating alopecia areata.
research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma on Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study
Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
research Platelet-Rich Plasma in Androgenetic Alopecia
PRP can help treat hair loss but needs standardized methods for best results.
research The Additive Value of Platelet-Rich Plasma to Topical Minoxidil in the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Combining PRP with Minoxidil improves hair density and thickness more than Minoxidil alone.
research iTRAQ-Based Quantitative Proteomics Revealing the Therapeutic Mechanism of a Medicinal and Edible Formula YH0618 in Reducing Doxorubicin-Induced Alopecia by Targeting Keratins and TGF-β/Smad3 Pathway
YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.
research Platelet-Rich Plasma in Hair Restoration
Platelet-rich plasma (PRP) is a promising treatment for hair loss, believed to extend the life cycle of hair follicles and prevent their shrinkage.
research The Association Between Androgenic Alopecia Severity and the Development of Metabolic Syndrome in Saudi Arabia: A Case-Control Study
There's a significant link between severe hair loss and metabolic syndrome in Saudi Arabia, suggesting early health checks could prevent future issues.
research Activation of Camp Signaling in Response to Alpha-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells
α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
research Paracrine Crosstalk Between Human Hair Follicle Dermal Papilla Cells and Microvascular Endothelial Cells
Cells from the base of hair follicles help blood vessel cells survive and grow, which is important for healthy hair.
research Effects of Flavonoid Derivatives on Human Microvascular Endothelial Cells
Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.
research Hair Follicle Germs Containing Vascular Endothelial Cells for Hair Regenerative Medicine
Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
research Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis
Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
research Perifollicular Vascularization: Cocultures and Tricultures Approaches to Study the Cross-Talk Between Microvascular Endothelial Cells, Follicle Papilla Cells, and Keratinocytes
Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
research Microarray Analysis Reveals Distinct RNA Expression Profiles in Endothelial Progenitor Cells Exposed to Pro-Inflammatory Environment or Oxidized LDL
Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
research A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(L-Lactide-Co-Caprolactone) for Endothelial Cells Delivery and Skin Wound Repair
The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
research In Vitro Culture Methods of Skin Cells for Optimal Skin Reconstruction by Tissue Engineering
New methods for growing skin cells can improve skin grafts by building blood vessels within them.
research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways
LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
research An Important Role of Cutaneous Lymphatic Vessels in Coordinating and Promoting Anagen Hair Follicle Growth
Skin lymphatic vessels are essential for hair growth.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold
The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.