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The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.

New culture method keeps human skin stem cells more stem-like.

Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.

Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.

Porphyra-334 may help reduce wrinkles and promote hair growth.

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.

Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.

In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Cellular and immunotherapies show promise for healing chronic wounds but need more research.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Skin aging reflects overall body aging and can indicate internal health conditions.

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.