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Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

Better hair loss models needed for research.

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

Tectoridin helps human hair cells grow and makes mouse hair longer, suggesting it could treat hair loss.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

PDCD4 is important for controlling skin cell growth and healing.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Skin stem cells in hair follicles are important for touch sensation.

New hair follicles could be created to treat hair loss.

miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.

MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.

Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.