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The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Finasteride may improve sperm count in subfertile men with low sperm count.

Finasteride increases hair count and improves hair growth with low risk of side effects.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.

New treatments targeting specific genes show promise for treating keratin disorders.

Stump-tailed macaque best for researching hair loss causes and treatments.

Camellia japonica extract may improve scalp health and promote hair growth.

Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Artificial skin is improving wound healing and shows potential for treating different types of wounds.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.