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This study found that exosome-incorporated human amniotic membrane scaffolds notably enhanced diabetic skin wound healing in mice, suggesting potential applications for ADSC-derived exosomes in clinical settings.

This study found that combining a human acellular amniotic membrane with iPSC-derived epithelial stem cells effectively repaired skin defects and promoted hair follicle formation in nude mice.

This review reports that the human amniotic membrane has promising regenerative, anti-inflammatory, and antimicrobial properties, suggesting its potential for innovative clinical applications in dermatology, such as wound healing and psoriasis treatment, as well as aesthetic uses like skin rejuvenation and hair regeneration.

In this study, decellularized human amniotic membrane was found to promote wound healing and reduce scar formation in rats with full-thickness skin defects, compared to traditional clinical treatments.

This comprehensive review suggests that CD44 signaling plays a significant role in post-natal skin wound healing and scar formation, with potential for therapeutic approaches targeting CD44 to shift from fibrotic scarring towards regenerative healing, including wound regeneration and hair neogenesis.

In this study, Wharton’s Jelly Mesenchymal Stem Cells, cultured with human platelet lysate, showed enhanced wound-healing capabilities and multilineage differentiation potential, distinguishing them from bone marrow-derived stem cells and presenting exciting prospects for regenerative medicine.

This study reported that exosomes derived from human amniotic mesenchymal stem cells (hAMSC-exo) accelerated hair growth in androgenetic alopecia mice by enhancing signals between hair follicle cells and improving cellular environments, particularly protecting against dihydrotestosterone-induced damage via Wnt/β-catenin signaling.

This article discusses the biology of cosmetic aging and the chemical pathways involved, emphasizing research advancements that aid clinicians in rejuvenating skin and increasing scalp hair density, but it provides no new results.

This study compared porcine-derived placental biomaterials with human-derived counterparts in a rat model of skin injuries and found no significant statistical differences in healing outcomes; however, porcine-derived materials showed reduced early inflammation and faster crust formation, suggesting potential advantages in healing effectiveness.

This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.

This study found that conditioned media from human amniotic fluid-derived stem cells may enhance skin regeneration by promoting cell proliferation and migration, and by modulating gene expressions altered by UV irradiation.

In this study, freezing gamma-irradiated amniotic fluid increased hair follicles and accelerated the transition to the anagen stage in rats, suggesting potential for treating hair loss safely and effectively.

This study suggests that the secretome from amniotic fluid-derived mesenchymal stem cells overexpressing Nanog could stimulate hair growth and increase follicle density, potentially aiding in alopecia treatment.

This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.

This study discusses treatment approaches for refractory Asherman syndrome, highlighting the potential role of CD133+ bone marrow-derived stem cells in conjunction with hysteroscopy for endometrial regeneration and improved pregnancy outcomes.

This study found that incorporating cell-adhesive ligands into 3D peptide hydrogels supports the survival and osteogenic differentiation of human amniotic mesenchymal stem cells.

This review explores regenerative treatment options for non-scarring alopecia, with a focus on the potential of mesenchymal stem cells for hair regrowth, but it reports no new clinical results.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

This review discusses various stem cell types, methods of obtaining them, their applications, and the potential use of exosomes, but reports no new clinical results.

In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.

In a study using a rat model of hypertrophic scars, researchers found that gamma-irradiated human amniotic fluid improved wound healing, collagen remodelling, immune response, and scar characteristics more effectively than saline or non-irradiated amniotic fluid, indicating its potential for clinical applications in scar management.

In this study, treatment with cell-derived nanovesicles from hair follicle mesenchymal stem cells improved photoaging signs in UVB-exposed mice and human dermal fibroblasts by reducing oxidative stress, enhancing cell proliferation, and promoting extracellular matrix production.

This study found that Wnt7a-containing conditioned medium from UC-MSCs can accelerate wound healing and promote hair follicle regeneration by enhancing specific cellular functions in the wound microenvironment.

This review highlights new perspectives in genomics and epigenomics for skin rejuvenation, comparing innovative strategies like senolytics and DNA repair modulators with classical treatments, and emphasizing the importance of tailoring therapies using individual genomic profiles for personalized anti-ageing approaches.

This study found that centrifugally spun scaffolds with higher concentrations of platelet-derived bioactive molecules enhanced melanocyte metabolic activity and proliferation, suggesting potential for improving vitiligo treatment.

This study found that human umbilical cord-derived mesenchymal stromal cell-conditioned media was safe and positively affected hair regeneration in 86.6% of participants in a pilot study.

This study reviewed the challenges of delivering nucleic acids for gene therapy, highlighting the limitations of non-viral vehicles and exploring bioinspired strategies using cell membrane camouflage for improved delivery efficacy.

This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.

This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.

This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.