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The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Hair loss drugs may cause sexual issues and infertility in men.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.

Green tea component EGCG could potentially promote human hair growth.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

High doses of finasteride cause cell growth and tumors in mice.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Method measures finasteride in plasma, suitable for pharmacokinetic studies.

Certain drugs change freshwater snail shells to a "banana" shape.

Finasteride boosts stem cell signals for hair growth.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.

Finasteride effectively treats BPH, but needs more trials to understand potential.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.